ID S2K3Q4_MUCC1 Unreviewed; 615 AA.
AC S2K3Q4;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000256|ARBA:ARBA00017887};
GN ORFNames=HMPREF1544_06370 {ECO:0000313|EMBL:EPB86845.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB86845.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KE123980; EPB86845.1; -; Genomic_DNA.
DR AlphaFoldDB; S2K3Q4; -.
DR STRING; 1220926.S2K3Q4; -.
DR VEuPathDB; FungiDB:HMPREF1544_06370; -.
DR eggNOG; KOG4362; Eukaryota.
DR InParanoid; S2K3Q4; -.
DR OMA; NQQRESC; -.
DR OrthoDB; 1362338at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd17720; BRCT_Bard1_rpt2; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031099; BRCA1-associated.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR13763:SF0; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; 1.
DR PANTHER; PTHR13763; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00292; BRCT; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50172; BRCT; 2.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 15..54
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 448..502
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 521..615
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 97..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 69195 MW; 7B0B29D0139BCF47 CRC64;
MEAEYVTNTE SCLECSICYS VFVQATNIAE CGHRFCLKCI QTSLKESSVC PTCQKPADIK
HLTADPRLDN VLGFIDTMKN AILSHPLTPL SLSLRQQQQQ HMSQRAQNMN TTSNSDETSE
MYQLEETSSD LIPSAEEIEQ SFSRKRKHTG VDTQNTDTQT TLNEEEDLER EFNDSVSAPT
TQDAKRFKPF ESGTVSQNLL STEDVDMAEK KPKITDDNEK KRLLNPKNIL GDIWSFSQDD
IDAAQSQSQQ NESSAMASVS GNSESEATQK GQQSASENHA LTDEPTSQAT QSAAITEASK
DFIPDTVYSD SEDDAGKQDV WECGNCEYVN RVYFQTCGCC RFFRNYKANT MLPAAEVDAN
IAAPPPPPKT TAKEPYKMTV AGDEENAPAE GTFTVPKTRR RTNSVSRKEV HIMYTGLTPE
DEKKLDKIKE EADLTLKIVI HYQMRDFNDV THVITSVDKK HLCKRTLKYL QGVLKGKWVV
DPQWLIDSTK SKKWQAEDKY EVQGDHLTGK THAPKLARES QQEPLFQDMK LYLFGDFTGK
HNKNDLLILC KAGGAKILSR KPPGHVARSK QALDLAEPIV IYSADQKKKK PVWLNQCQVR
DPQWIIDCIS KFKVE
//
