ID S2KGD7_MUCC1 Unreviewed; 680 AA.
AC S2KGD7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Amino acid transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF01490};
GN ORFNames=HMPREF1544_01778 {ECO:0000313|EMBL:EPB91455.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB91455.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC {ECO:0000256|ARBA:ARBA00008066}.
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DR EMBL; KE123909; EPB91455.1; -; Genomic_DNA.
DR AlphaFoldDB; S2KGD7; -.
DR STRING; 1220926.S2KGD7; -.
DR VEuPathDB; FungiDB:HMPREF1544_01778; -.
DR eggNOG; KOG1304; Eukaryota.
DR InParanoid; S2KGD7; -.
DR OMA; YWCYYIL; -.
DR OrthoDB; 3601817at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF666; VACUOLAR AMINO ACID TRANSPORTER 3; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 308..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 606..627
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 276..660
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT REGION 26..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 75781 MW; 0CF7055FAD6AF227 CRC64;
MERSVTIDLP VEQVAKVVKR HLVYHPASSS SSLIPPHPSH KQRQQRKQQQ KQKKEQKLKQ
QQQQQQQQQG QKKQPTYSTH HLLPGGSILD EIYKWTAQVE NKQQKRSRTQ SISLPAHREP
TIDVSLQSLK QPGGFRRHYV LSKAAKQGKK PPNFVTSSFV EFLCLYGHFG GENLSEAESS
SSDSSSDSYH SSEDDNGGGA SSEDDSIPEG GIMAYRPPLN NASYSYGATD ATQGSPLPIS
TNTKRSLVPL QYKQLQARET MPLLSRSRPG QTLQGKATPG KAMFLLLKSF VTTGIMFLPK
AFYNGGLLFS IFAIIAWALI SLWSFLLLVQ TRLVVPASFG DMGGVLYGSR MRVAVLVAIT
LSQIGFVCAY MIFVAENLQS LVLTFSKCRL TIPMHLLILA QSFAFIPLAM IRKIQRLSVF
ALIADVFIVI GLIYLFYYDL KELFSIGMVQ VEMWNPLHYP LFLGTAAFTF EGIGLVIPIT
ESMKDPKKFP RVLTRALIVI TCLFITMGAL SYMTFGENVQ TIILLNLPSK DPMVSSIQTL
YSLAICLSIP LQLFPAIRIM ENGLFTTKSG KNNAIVKWQK NVFRVFVVFL CAGIGIIGSK
DKLDKFVALI GALFCIPLCF VFPPLFHLKA LELPTTRRIA NFALILFGII CMAFVSFSTI
TQWNSAEPTD PVQRCIIHRA
//
