ID S2W1Y2_9ACTN Unreviewed; 836 AA.
AC S2W1Y2;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF9306_01914 {ECO:0000313|EMBL:EPD32345.1};
OS Propionimicrobium lymphophilum ACS-093-V-SCH5.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Propionimicrobium.
OX NCBI_TaxID=883161 {ECO:0000313|EMBL:EPD32345.1, ECO:0000313|Proteomes:UP000014417};
RN [1] {ECO:0000313|EMBL:EPD32345.1, ECO:0000313|Proteomes:UP000014417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-093-V-SCH5 {ECO:0000313|EMBL:EPD32345.1,
RC ECO:0000313|Proteomes:UP000014417};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Propionimicrobium lymphophilum ACS-093-V-SCH5.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD32345.1}.
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DR EMBL; AGZR01000009; EPD32345.1; -; Genomic_DNA.
DR RefSeq; WP_016456720.1; NZ_KE150269.1.
DR AlphaFoldDB; S2W1Y2; -.
DR STRING; 883161.HMPREF9306_01914; -.
DR PATRIC; fig|883161.3.peg.1902; -.
DR HOGENOM; CLU_005070_4_1_11; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000014417; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000014417};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 424..459
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
SQ SEQUENCE 836 AA; 92760 MW; C47EE9B7D2773C00 CRC64;
MFERFTDRAR RVVVLAQDEA KMLNHNYIGT EHLLLGLIHE GEGVAAKALE QLGISLEAVR
EQVEEMIGHG QTEPAGHIPF TPRAKKVLEL SLREALQMNH SYIGTEHILL GLIREGEGVA
ATVLIKLGAD LNRVRSTVLQ LLSGYQGGAE GDLATSGAPQ DTPRSGSSIL DQFGRNLTQA
ARENRLDPVI GRKKEIERVM TVLSRRTKNN PVLIGEPGVG KTAVVEGLSQ QIVRGDVPET
LRNKQIYTLD LGSLVAGSRY RGDFEERLKK VLKEIQRRGD VMLFIDEIHT LVGAGAAEGA
IDAASILKPM LARGELQTIG ATTLEEYRKY IEKDAALERR FQPIQVDEPS VELTVDILKG
LRDRYEAHHR ITITDDALEA AARLAARYIQ DRFLPDKAID LIDEAGARMR IQRMTAPPDL
REFDEKISKV RLEKEAAIDQ QDFERAAGLR DQEKNLIAER NERESAWREG DSDTPAVIGE
EQIAEVLSTT TGVPVSQITE EESTRLLHME EEIHKRYVGQ DEAVKALSRS IRRARAGLKD
PNRPSGSFIF AGPSGVGKTE LTKALAEFLF GDEDALITLD MSEYSEKHTA SRMFGSPPGY
VGYDEGGQLT EKVRRKPFSV ILFDEIEKAH PDIFNSLLQI LDEGRLTDAQ GRVVDFKNTV
IVMTTNLGTK DISRSVSLGF SNSGKAGNDY ETMKSKVNEE LKQHFRPEFL NRVDEVVVFH
QLTEEEIANI VSLMVGQVEK RLAERDMGIE LTPAASKLIA EIGYDPLLGA RPLRRAIQSK
IEDPIAEQIL FGEVKAGSIV VVDVAEGADK DSAEPFVFRT APKLEEIDHL PENTEN
//
