ID S2WW55_9ACTN Unreviewed; 856 AA.
AC S2WW55;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Rne/Rng family ribonuclease {ECO:0000313|EMBL:EPD31954.1};
GN ORFNames=HMPREF9306_01512 {ECO:0000313|EMBL:EPD31954.1};
OS Propionimicrobium lymphophilum ACS-093-V-SCH5.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Propionimicrobium.
OX NCBI_TaxID=883161 {ECO:0000313|EMBL:EPD31954.1, ECO:0000313|Proteomes:UP000014417};
RN [1] {ECO:0000313|EMBL:EPD31954.1, ECO:0000313|Proteomes:UP000014417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-093-V-SCH5 {ECO:0000313|EMBL:EPD31954.1,
RC ECO:0000313|Proteomes:UP000014417};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Propionimicrobium lymphophilum ACS-093-V-SCH5.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD31954.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGZR01000009; EPD31954.1; -; Genomic_DNA.
DR RefSeq; WP_016456336.1; NZ_KE150269.1.
DR AlphaFoldDB; S2WW55; -.
DR STRING; 883161.HMPREF9306_01512; -.
DR PATRIC; fig|883161.3.peg.1500; -.
DR HOGENOM; CLU_003468_2_2_11; -.
DR OrthoDB; 9804278at2; -.
DR Proteomes; UP000014417; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014417};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 444..527
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 821..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..284
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..856
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 94505 MW; DFDD916BE8695A76 CRC64;
MAEKLDIAGQ DPAASQDPDL PRPPSGRRAA SRPAGPPSQT SKNTNLSAES LYDAPKPASD
SSDNGDFKKE ESKPANQRVS RSRRRNSSSS ASSDVKASDE VQGNVAESNS DEKSSAEASS
QDQNKQSQNN RRGSRRSSSR NDSDSKNQSR RRRRRQTPAA ETEPSAELEA KLDEVLGAKK
AAHKDGDHKS ASELLGGKVP TNELGEIDKE AALADLTATI AGKTSNSDAE PSNVKHKSAN
KSKTGESVSA KKNQEEPSDA DQQKKDSAEN SEEEKDDNSS NGLRRRRRRG GRRRHGSSND
DSDESNNSDE AKEDAKDEKS EEDNNQQSSG SHRRRRRRRR GGSSSDDDTT IAIRQPRSRS
VSDEITSIEG STRLEAKRQR RREGRSQRRR APILTEAEFL ARRENVSRKM VIRQSDDYTQ
LAVLEDNMLV EHYVDRKNST SLIGNIYLGR VQNVLPSMEA VFIDIGRGRN AVLYAGEVNW
DAFEVASDKR QVEQVFKSGD SVIVQVSKDP VGAKGARLTG HVSLPGRYVV YSPNGHLSGI
SRKLPDKERA RLKKILDETL SDSASVIVRT AAEGATEENL IHDVDRLKAQ WEVIEKKAKR
GGAPAQLYAE PDLTLRTIRD IFTEDFEELI IAGQGSQNDA WESVSQYVEM IAPQLADRLK
KWDSQKQGDL FSVYRIDEQI SKALERKVFL PSGGSLVIDR TEAMTVIDVN TGKFTGSGGN
LEETVTKNNL EAAEEIVRQL RLRDLGGIIV VDFIDMVLPA NRDLLLRRLV ECLSRDRTRH
QVSEVTSLGL VQMTRKRIGT GLAEAFTTEC EACGGRGYHR YDTPVASQAP ADGGERHGRK
NGRKNSKNGK GKNKNN
//
