ID S2XMA5_9BACL Unreviewed; 445 AA.
AC S2XMA5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Aminopeptidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1210_02271 {ECO:0000313|EMBL:EPD51080.1};
OS Paenisporosarcina sp. HGH0030.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae;
OC Paenisporosarcina.
OX NCBI_TaxID=1078085 {ECO:0000313|EMBL:EPD51080.1, ECO:0000313|Proteomes:UP000014412};
RN [1] {ECO:0000313|EMBL:EPD51080.1, ECO:0000313|Proteomes:UP000014412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGH0030 {ECO:0000313|EMBL:EPD51080.1,
RC ECO:0000313|Proteomes:UP000014412};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Paenisporosarcina sp. HGH0030.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD51080.1}.
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DR EMBL; AGEQ01000012; EPD51080.1; -; Genomic_DNA.
DR RefSeq; WP_016428779.1; NZ_KE150421.1.
DR AlphaFoldDB; S2XMA5; -.
DR STRING; 1078085.HMPREF1210_02271; -.
DR PATRIC; fig|1078085.3.peg.2262; -.
DR eggNOG; COG2234; Bacteria.
DR HOGENOM; CLU_024336_3_0_9; -.
DR Proteomes; UP000014412; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02133; PA_C5a_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR045175; M28_fam.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR PANTHER; PTHR12147:SF26; ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1; 1.
DR PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022438};
KW Protease {ECO:0000256|ARBA:ARBA00022438};
KW Reference proteome {ECO:0000313|Proteomes:UP000014412};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..445
FT /note="Aminopeptidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004503436"
FT DOMAIN 132..214
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 242..431
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
SQ SEQUENCE 445 AA; 48326 MW; 422914C73D94FC16 CRC64;
MKNKFYKFAI GAILCLSVIA PIATFATHYT STQNEKETNL ETKILQSLDA DNMYNNIKFL
SKTPRVAGTQ QEDAAVAYIK KQFESYGYKA EVQAFTFNDY TAPNSIGLDV ERFSKKLNPQ
ALEYSVSGKA TAEVIFAGLG QKNDIAQLDL TGKIILLQRG VISFKEKMLN VAAKGAAGVI
FYNNAPGTIM GSLGEPNKAY VPSVLLTQTE GEAILIHLNK NPRAVVSLNI EGAKSAQNTS
HNVIATKKPN VSNKASHDIL VIGAHHDSVA SAPGANDDAS GTAMTLELAR VLKTIPTDTE
IRFITFGAEE LGLLGSNHYV EQLPKNEISR IVANFNLDMV GSKDAGELIL QTVDNKPNLV
TELAQDASTQ LNGAPTPYNQ GDSSDHVPFS KAGIPAALFI HNPAEPWYHK PQDTIDKISK
EKLQDVSEIV SIAVWNQIKI DRQVK
//
