ID S2XTA6_9ACTN Unreviewed; 488 AA.
AC S2XTA6;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Histidine kinase domain-containing protein {ECO:0000259|PROSITE:PS50109};
GN ORFNames=HMPREF1211_08139 {ECO:0000313|EMBL:EPD55236.1};
OS Streptomyces sp. HGB0020.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1078086 {ECO:0000313|EMBL:EPD55236.1, ECO:0000313|Proteomes:UP000014410};
RN [1] {ECO:0000313|EMBL:EPD55236.1, ECO:0000313|Proteomes:UP000014410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGB0020 {ECO:0000313|EMBL:EPD55236.1,
RC ECO:0000313|Proteomes:UP000014410};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Streptomyces sp. HGB0020.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD55236.1}.
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DR EMBL; AGER01000033; EPD55236.1; -; Genomic_DNA.
DR RefSeq; WP_016437924.1; NZ_KE150431.1.
DR AlphaFoldDB; S2XTA6; -.
DR STRING; 1078086.HMPREF1211_08139; -.
DR PATRIC; fig|1078086.3.peg.8195; -.
DR HOGENOM; CLU_045351_1_0_11; -.
DR OrthoDB; 9767435at2; -.
DR Proteomes; UP000014410; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.280; GAF domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR038424; H_kinase_PdtaS_GAF_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR022066; PdtaS_GAF.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF23; SENSOR HISTIDINE KINASE PDTAS-RELATED; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF12282; PdtaS_GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014410}.
FT DOMAIN 290..486
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 488 AA; 53680 MW; 66733588A61C5504 CRC64;
MNELVRQHTA LDDSDLEWLH LLVSEWQLLS DLSFADLVLW VPTRDGTRYV SVAQMRPNTG
PTSYQDDMVG HLVPRGRRPM LDAALDEGRI VREGDPEWRE EVPVRVESIP VRREGRVLGV
IARNTNLLTV RTPSRLELTY LQSASDLAQM IAAGSFPFAN QQMDMDAAPR VGDGLIRLDA
DGTVQYASPN ALSAYHRMGL ASDLVGQNLG LTTAELAPTR GPVDEALAKV ASGWAPREFE
IEAHDGVIQF RAIPLKPKGT RIGSLVLLRD VTELRRRERE LITKDATIRE IHHRVKNNLQ
TVAALLRLQA RRIESERGRD ALEEAVRRVG SIAIVHETLS QNLDERVEFD EIADRVLAMV
AEISPGKVTG RRSGRFGILD AEVATPLSMV LTEVLQNALE HGFREGETGT VEVSAVRGGT
AKESRLLVTV QDDGVGLPEG FDPHTSGNLG LQIVRTLVVG ELGGTFDMVP APERGTRVIL
DVPVPAHK
//
