ID   S2Y894_9ACTN            Unreviewed;       488 AA.
AC   S2Y894;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPD60316.1};
GN   ORFNames=HMPREF1211_05064 {ECO:0000313|EMBL:EPD60316.1};
OS   Streptomyces sp. HGB0020.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1078086 {ECO:0000313|EMBL:EPD60316.1, ECO:0000313|Proteomes:UP000014410};
RN   [1] {ECO:0000313|EMBL:EPD60316.1, ECO:0000313|Proteomes:UP000014410}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HGB0020 {ECO:0000313|EMBL:EPD60316.1,
RC   ECO:0000313|Proteomes:UP000014410};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA   Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Streptomyces sp. HGB0020.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPD60316.1}.
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DR   EMBL; AGER01000019; EPD60316.1; -; Genomic_DNA.
DR   RefSeq; WP_016434979.1; NZ_KE150428.1.
DR   AlphaFoldDB; S2Y894; -.
DR   STRING; 1078086.HMPREF1211_05064; -.
DR   PATRIC; fig|1078086.3.peg.5114; -.
DR   HOGENOM; CLU_019399_4_1_11; -.
DR   OrthoDB; 99456at2; -.
DR   Proteomes; UP000014410; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06543; GH18_PF-ChiA-like; 1.
DR   Gene3D; 2.60.40.290; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001919; CBD2.
DR   InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf.
DR   InterPro; IPR012291; CBM2_carb-bd_dom_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR42976; BIFUNCTIONAL CHITINASE/LYSOZYME-RELATED; 1.
DR   PANTHER; PTHR42976:SF1; GH18 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00553; CBM_2; 1.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00637; CBD_II; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49384; Carbohydrate-binding domain; 1.
DR   PROSITE; PS51173; CBM2; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014410};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..37
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           38..488
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004516019"
FT   DOMAIN          33..141
FT                   /note="CBM2"
FT                   /evidence="ECO:0000259|PROSITE:PS51173"
FT   DOMAIN          194..488
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
FT   REGION          140..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   488 AA;  49722 MW;  E063DD2D26B339B3 CRC64;
     MSTHRRKVSG RSKAIGAVVA AAVVGGGAFA LTGVAQAAGV GAAYTKTSDW STGYTAQYVV
     TNNTGSTEKD WKLEFDLPAG AKLSSLWNAE SSVSGQHVTV TPAKWDTDGL APGKSVTVGF
     VVNGSADPKS CLIDGAKCSA DDGATPEPSG RPTESATPTQ KPTATPTPTK TSTPTSTPTA
     TPSQSSGTGT KASAGFSPYV DTSLYPAFDL VASADATGVK NYNLAFITDG GGCTPKWGGV
     TDLGSDGVAS QIGALRAKGG DVRVSFGGAS GSELATTCSS ADALAAAYGK AVDQFKLTKV
     DFDIEGGALP NTTANTNRAK AIAKLQQQHP DLDVSFTLPV MPEGLTQDGV NLLSNAKSNG
     VKINAVNIMA MDYGASYSGD MGTYAEQAAT ATQAQIKGVL GLSDADAWKT VAVTPMLGVN
     DVSSEIFKVD DATQLVDFAK SKGLGWLSMW SATRDKQCDG GAKPTADATC SSIVQDKFAF
     SKAFAAFN
//