ID S2YU13_9ACTN Unreviewed; 680 AA.
AC S2YU13;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Peptidase S53 domain-containing protein {ECO:0000259|PROSITE:PS51695};
GN ORFNames=HMPREF1211_08127 {ECO:0000313|EMBL:EPD55224.1};
OS Streptomyces sp. HGB0020.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1078086 {ECO:0000313|EMBL:EPD55224.1, ECO:0000313|Proteomes:UP000014410};
RN [1] {ECO:0000313|EMBL:EPD55224.1, ECO:0000313|Proteomes:UP000014410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGB0020 {ECO:0000313|EMBL:EPD55224.1,
RC ECO:0000313|Proteomes:UP000014410};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Streptomyces sp. HGB0020.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD55224.1}.
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DR EMBL; AGER01000033; EPD55224.1; -; Genomic_DNA.
DR RefSeq; WP_016437912.1; NZ_KE150431.1.
DR AlphaFoldDB; S2YU13; -.
DR STRING; 1078086.HMPREF1211_08127; -.
DR PATRIC; fig|1078086.3.peg.8180; -.
DR HOGENOM; CLU_012501_0_0_11; -.
DR OrthoDB; 151889at2; -.
DR Proteomes; UP000014410; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 1.
DR CDD; cd04056; Peptidases_S53; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR006644; Cadg.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR030400; Sedolisin_dom.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR14218:SF42; PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14218; PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2; 1.
DR Pfam; PF05345; He_PIG; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00736; CADG; 1.
DR SUPFAM; SSF49313; Cadherin-like; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51695; SEDOLISIN; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014410};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..680
FT /note="Peptidase S53 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004504512"
FT DOMAIN 107..439
FT /note="Peptidase S53"
FT /evidence="ECO:0000259|PROSITE:PS51695"
FT REGION 294..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 68756 MW; 739005621F3B3E35 CRC64;
MREKPRRSLR RLLTAVIPAL ALGLAGLAAA PTAQAQVHPD SRVTQNAKAL TSPDRQIFHS
TGKAGQKVPT THLCAAAQPG HASCFAQRRT DIKQRLASAL AAAAPSGLSP ANLHSAYNLP
STGGSGLTVA VVDAYNDPNA ESDLATYRSQ FGLSACTKAN GCFKQVSQTG STTSLPSNDT
GWAGEEALDI DMVSAVCPNC SIILVEAKSA NDSDLGTAEN EAVALGAKVV SNSWGGDEAS
SQTSEDTAYF KHPGVAITVS AGDEDYGAEY PATSQYVTAV GGTALSTSSN SRGWTESVWK
TSGSEGTGSG CSAYDPKPSW QTDTGCSRRM ESDVSAVADP ATGVAVYDTY GGSGWAVYGG
TSASAPIIAG VYALAGTPGS GDYPAKYPYS HTSNLYDVTS GNNGSCSTSY FCTARTGYDG
PTGWGTPNGT TAFTAGSDSA NTVSVTDPGS QSTTTGGSVS LQIHATDSAG AALTYSASGL
PTGLSINAST GVISGTASTA GTYQVTVTAT DGTGASGSAS FTWTVGTSGG GCASSQLLGN
QGFESGNTGW TATSGVITDD NGQAPHGGSY YAWLDGYGTT HTDTLSQSVT VPAGCKATFT
FYLHIDSAET GSTAYDKLTV TAGSRTLATY SNVNAASGYA QKSFDLSSYA GSTVTLKFSG
TEDSSLQTSF VVDDTAVTTS
//
