ID S2YWN7_9ACTN Unreviewed; 284 AA.
AC S2YWN7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=HMPREF1211_07307 {ECO:0000313|EMBL:EPD56189.1};
OS Streptomyces sp. HGB0020.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1078086 {ECO:0000313|EMBL:EPD56189.1, ECO:0000313|Proteomes:UP000014410};
RN [1] {ECO:0000313|EMBL:EPD56189.1, ECO:0000313|Proteomes:UP000014410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGB0020 {ECO:0000313|EMBL:EPD56189.1,
RC ECO:0000313|Proteomes:UP000014410};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Streptomyces sp. HGB0020.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD56189.1}.
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DR EMBL; AGER01000030; EPD56189.1; -; Genomic_DNA.
DR RefSeq; WP_016437168.1; NZ_KE150430.1.
DR AlphaFoldDB; S2YWN7; -.
DR STRING; 1078086.HMPREF1211_07307; -.
DR PATRIC; fig|1078086.3.peg.7361; -.
DR HOGENOM; CLU_055284_1_0_11; -.
DR OrthoDB; 2339873at2; -.
DR Proteomes; UP000014410; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF81; PNPLA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000014410}.
FT DOMAIN 11..204
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 284 AA; 29307 MW; 4CD5A6855116F779 CRC64;
MSGDTSGTAL VLGGGGPVGG AWLTGVLAGL TDAGVDLGRA DVIIGTSAGA VFGSRLACGQ
PPRELYERQL SGADRIELRV TAAQTLRFLW AALGSRDPER SVRRLGRAAL SAARTAPAAE
LHDAVRELLR GATDWPARAL RIAAVDAVSG EVAAFDADSK TDLVDAVAAS CAVPLLWPPV
ELDGRRFIDG GSRATANLQL AAGHRRVLAV VPIPDAVGPH PSARQQATDL TARGTTVTLL
CPDHTARRAM GRNMTTTTRM PAAARAGHAQ GTALANTVAK TWHA
//
