ID   S2YYU1_9ACTN            Unreviewed;       124 AA.
AC   S2YYU1;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Anti-sigma factor antagonist {ECO:0000256|RuleBase:RU003749};
GN   ORFNames=HMPREF1211_06718 {ECO:0000313|EMBL:EPD56989.1};
OS   Streptomyces sp. HGB0020.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1078086 {ECO:0000313|EMBL:EPD56989.1, ECO:0000313|Proteomes:UP000014410};
RN   [1] {ECO:0000313|EMBL:EPD56989.1, ECO:0000313|Proteomes:UP000014410}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HGB0020 {ECO:0000313|EMBL:EPD56989.1,
RC   ECO:0000313|Proteomes:UP000014410};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA   Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Streptomyces sp. HGB0020.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC       {ECO:0000256|ARBA:ARBA00009013, ECO:0000256|RuleBase:RU003749}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPD56989.1}.
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DR   EMBL; AGER01000028; EPD56989.1; -; Genomic_DNA.
DR   AlphaFoldDB; S2YYU1; -.
DR   STRING; 1078086.HMPREF1211_06718; -.
DR   PATRIC; fig|1078086.3.peg.6780; -.
DR   HOGENOM; CLU_115403_3_3_11; -.
DR   Proteomes; UP000014410; Unassembled WGS sequence.
DR   GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR   CDD; cd07043; STAS_anti-anti-sigma_factors; 1.
DR   Gene3D; 3.30.750.24; STAS domain; 1.
DR   InterPro; IPR003658; Anti-sigma_ant.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   NCBIfam; TIGR00377; ant_ant_sig; 1.
DR   PANTHER; PTHR33495; ANTI-SIGMA FACTOR ANTAGONIST TM_1081-RELATED-RELATED; 1.
DR   PANTHER; PTHR33495:SF2; ANTI-SIGMA-B FACTOR ANTAGONIST; 1.
DR   Pfam; PF01740; STAS; 1.
DR   SUPFAM; SSF52091; SpoIIaa-like; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014410}.
FT   DOMAIN          15..118
FT                   /note="STAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50801"
SQ   SEQUENCE   124 AA;  13308 MW;  F45727286721C6BF CRC64;
     MAFYVIGDEQ GDWTVLSVSG ELDLVTSPVL RQRVHDVVAD GRHSLVLDLS EVFFCDSSGV
     GVLIASRRLI RSCQGSLRLI LPAQGAEDGS HVNRVLGALG VRRLFDVYAD VEDAVTEQAG
     PLSA
//