ID S3C3C4_OPHP1 Unreviewed; 513 AA.
AC S3C3C4;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Purine-cytosine permease fcy22 {ECO:0000313|EMBL:EPE06276.1};
GN ORFNames=F503_02404 {ECO:0000313|EMBL:EPE06276.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE06276.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE06276.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE06276.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
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DR EMBL; KE148153; EPE06276.1; -; Genomic_DNA.
DR AlphaFoldDB; S3C3C4; -.
DR STRING; 1262450.S3C3C4; -.
DR VEuPathDB; FungiDB:F503_02404; -.
DR eggNOG; ENOG502QQ8Y; Eukaryota.
DR HOGENOM; CLU_026016_2_0_1; -.
DR OMA; RRYINIC; -.
DR OrthoDB; 65220at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR PANTHER; PTHR31806:SF5; PURINE-CYTOSINE PERMEASE FCY21; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
DR PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR002744}.
FT TRANSMEM 77..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 55045 MW; D390C333747273F8 CRC64;
MSTDPEKGIA PVVSSDVELG SSQEHKSRSH DGEVHDDFHV PAVGQPFWQR LSNAGFELRG
VEPVPVEKRT DTRYLNVFTI FGTSMTSLLP VGIGAVTTIG YGLSLRDASL MIVFLQFLFG
LPAAYIITLG PLTGMRQMIQ SRYCFGKYIN ILTTVITTLT IGGFAVTGSV NGAECLAYVR
QGTLSVDGAI AIIMCSSMVI SCLGYYVLHQ FTRWAWIPTL FALVVLVGCA GDQLWQQTPQ
AASVESRQGY LGIVALLAGN MVSWGNVASD VACYMPPTAP RLRVALYCLL GISGPFSVLM
VLGAAIGGAM PQIPAWADAY STHGTGGVLG VILIARLGDF GRFILVILGM SVLATCARDI
YSVSFNIICI VPWLRRVPRV VLAIVATGTI IGVAHRAAQD MVSAIITFLS IIGYYAGSSV
TCFLIEFLYF RKGDPASFNP AIWDDGRKLP TGLSALVGVL VPWALIAPAM DQAWYTGPIA
EKVGDLGFEF AVILSALVYP PVRALEIKIR GRL
//
