ID S3C452_OPHP1 Unreviewed; 663 AA.
AC S3C452;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=G-protein coupled receptor {ECO:0000313|EMBL:EPE08274.1};
GN ORFNames=F503_01057 {ECO:0000313|EMBL:EPE08274.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE08274.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE08274.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE08274.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE148149; EPE08274.1; -; Genomic_DNA.
DR AlphaFoldDB; S3C452; -.
DR STRING; 1262450.S3C452; -.
DR VEuPathDB; FungiDB:F503_01057; -.
DR eggNOG; ENOG502RY0W; Eukaryota.
DR HOGENOM; CLU_026939_1_0_1; -.
DR OMA; VRPSMSF; -.
DR OrthoDB; 1360712at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR PANTHER; PTHR42058:SF1; -; 1.
DR PANTHER; PTHR42058; G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EPE08274.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 57..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..237
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 440..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 71328 MW; 23F1BDBA72F9E347 CRC64;
MSCIAPFLPA ADYINSTGYI SGRFCSEATG TTCCLPCPLT EWVYPDSFSS LTTATDWVAV
ASTLCCVFLL ISWLVLPVDK TNRHYLSICL TTGVLFMNLG FIVPLAAQPN QCADAITPNG
MKSNAACAAS GSFLILGGWS AVVWVFLRSL SLHLQICWQV VVGRTFMWVA QFAGWGVPVL
GLILALVLSG LSFRFGTTCH INHGNSLAVL WIPLLAVSSI TIVVQLVTFA YCIKVYLVSL
ADNSASTEGS GLPSYSNSIR TMTPRQAYRR VRRVIQLQWR GIAIVLIIVT DVIFFSVVFV
FQDNTVAAVS RDPAKANNWL FCLATNSSDK SKCLQYAASF TVNEATIGAV LILLAMNGFW
LLFLLGRWSM VHGWIDLFTP AAKLNNKREF VSVDARMDDL KKDTRSYEML SRDVSSSVPE
AGGPRTAITT TTSSILKKEH DPVTSFSSSP TGAASRAMPN SAMTANRSPS ALSHKTPGFE
LVTALSPVAQ SKSGFDLDEA HDSPSPLMDL NTAAMGGAGI MNTATGHGRY GSHSSFTSYN
NTTTISSGGA PAATNATNNS SVPSGRRTPD YFGQTARYNA PARSFSNPRP PTSSSVNSPP
GTSGRWDSRD SFARAASPPH GSNGVRTHSR FGSRNESRTR NANGGDDDFN DIENRHPLGM
NRI
//
