ID S3C5A7_OPHP1 Unreviewed; 973 AA.
AC S3C5A7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Origin recognition complex subunit 4 {ECO:0000313|EMBL:EPE08679.1};
GN ORFNames=F503_04266 {ECO:0000313|EMBL:EPE08679.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE08679.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE08679.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE08679.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ORC4 family.
CC {ECO:0000256|ARBA:ARBA00005334}.
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DR EMBL; KE148148; EPE08679.1; -; Genomic_DNA.
DR AlphaFoldDB; S3C5A7; -.
DR STRING; 1262450.S3C5A7; -.
DR VEuPathDB; FungiDB:F503_04266; -.
DR eggNOG; KOG0955; Eukaryota.
DR eggNOG; KOG2228; Eukaryota.
DR HOGENOM; CLU_007115_1_2_1; -.
DR OrthoDB; 230201at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15492; PHD_BRPF_JADE_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR000637; HMGI/Y_DNA-bd_CS.
DR InterPro; IPR016527; ORC4.
DR InterPro; IPR032705; ORC4_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12087; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR12087:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF14629; ORC4_C; 1.
DR Pfam; PF13831; PHD_2; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00354; HMGI_Y; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 336..386
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 107..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 973 AA; 103388 MW; D1F1A3D466094B8D CRC64;
MSGINGSRKR ARSDADDVDA DATTADTATS VSTTTTGIKR QRLANEPPSI VVNGGSHGAA
DTTHGAGRLS ALATTPKTPR TVHAMASAIT GALAYGVGSL VGGGRMRGKS VSNQHGATLV
PRSLASSHNE TGTPETGAQM LNDIMGGDVD AEGFLDPDAT DTEMPETPTS KKPASVARRS
SQQPKGRRNV TDANPAQDDD KEENATLVGS ASPTSDTPSK NPLRAPLLAE AGTTETPAAT
TTPAKKRGRK PKDPSQPTTL RKTPAKGTAS ARKNATPKAA TPNGDAPIKR GRGRPRKHPI
VEEDPILKLA QAKARSLAKQ QLLQQQKAVD EDDGSGEVCL ICSKPDSEPP NEIILCETCD
LAVHQQCYNV PVIPEGDWFC KNCVRKQEHE KQLQKRASET PAGDETEEET GTDRQPLEPP
TAHEKDDLAA ELVAATPPRD LAPDIANFES HLSKTKRILL GRCTGRHRVR LHGQDEAYDK
VYQVVEQTVV AGEGNSMMVI GARGTGKTTM VETILDDLAA EHGGAFHVVR LNGFIHTDDK
LALREIWRQL GKEMAVDDDV VSKTNNYADT LASLLALLSH PSEIQAAAVG SGAETATSAP
AVTSTSVVFI MDEFDLFATH ARQTLLYNLF DIAQARKAPI AVLGLTTKID VVESLEKRVK
SRFSHRYVYL SLPRSLPAFW DVCRYGLVVE EPSDTKDGVM AVDIVQEEGH AAFQQWWKHM
IDTAKDDSTF QEQLEFHFYS NKSIPAFWTT CVMPLVAVSS AAPRLRLPPV GCNNTAATTE
VVRSVGRPSL AAAAASSAAI ANAGKSFEEV PPLPLAAPDS KLHLLASLSE LELSLLITAA
RLDIVLSTDT VNFAMAYDEY VSLMGKQRVQ SSLASSGVVG IGGAGAMGGG LVIGGGARVW
GRGVASRAWE RLAALGLLIP AGMGANSRGR PGALITSGLE GRSMWRSEVS LEEIPAAPGV
KLGAVLGRWC KEI
//
