ID S3CC16_OPHP1 Unreviewed; 376 AA.
AC S3CC16;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Vacuolar iron transporter ccc1 {ECO:0000313|EMBL:EPE10447.1};
GN ORFNames=F503_05542 {ECO:0000313|EMBL:EPE10447.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE10447.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE10447.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE10447.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CCC1 family.
CC {ECO:0000256|ARBA:ARBA00007049}.
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DR EMBL; KE148146; EPE10447.1; -; Genomic_DNA.
DR AlphaFoldDB; S3CC16; -.
DR STRING; 1262450.S3CC16; -.
DR VEuPathDB; FungiDB:F503_05542; -.
DR eggNOG; KOG4473; Eukaryota.
DR HOGENOM; CLU_038957_0_2_1; -.
DR OMA; RWSIALC; -.
DR OrthoDB; 1357at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR InterPro; IPR008217; Ccc1_fam.
DR PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR PANTHER; PTHR31851:SF52; PROTEIN CCC1; 1.
DR Pfam; PF01988; VIT1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 254..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 40559 MW; A512605F4777630A CRC64;
MADSSRYSRL APDNGSPYSL GALSTSSSNI SHHDDNESED SIPMTRRDAP PRARRAPKNP
KPKSAAPRTR YLPTSRRFWA DFTMGFADGL TVPFALTAGL SSLGQTDTVV YAGLAEVSAG
CISMGIGGYL SARQSSPSTS STRDDNVEDE DDDTSCKDLE AFRSSGEDHE KDATASPTAV
HPSALASRYL APLNLPADLQ QLVMTHIAAK PDTIQALLAA ESQTLSDPDY GHYSEQRALL
DERESDADDD DDDYVWPVAS GLSVALGYLI GGLLPLGPYF FVESVGNGLR WSFAVCIVAL
FLFGFLRDFA LGSQAAADSG SARKTSARQL SWHKSQIPWR RLWKSTFEGL QMVILGAIAA
IAAVLCVRMF ESEKST
//
