ID S3CD97_OPHP1 Unreviewed; 601 AA.
AC S3CD97;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Trichothecene efflux pump {ECO:0000313|EMBL:EPE04253.1};
GN ORFNames=F503_04768 {ECO:0000313|EMBL:EPE04253.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE04253.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE04253.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE04253.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE148162; EPE04253.1; -; Genomic_DNA.
DR AlphaFoldDB; S3CD97; -.
DR STRING; 1262450.S3CD97; -.
DR VEuPathDB; FungiDB:F503_04768; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_000960_25_2_1; -.
DR OMA; FGRRWFI; -.
DR OrthoDB; 2663368at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06179; MFS_TRI12_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR010573; MFS_Str1/Tri12-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF109; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF06609; TRI12; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..530
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 63438 MW; 1066358C5388677B CRC64;
MAETNGGTTA ESNTAPAAHS PRNTETAVSD AEKATVEHGT VSTTPATPHG AWIPDSDDEY
EVTFKTWIVV FILSASYGIS FWIVPALSSC ATTVATLLGD TSAAAWYISI YLVTITIAFM
ICGANSDLFG RRWFITGGNA LLFVGFIVGG SARSNTAMLA AMGLIGFGAG NAQLAAFALP
ELLPNKWRHI AIVIADLFVL FSAVVGPVAG RFAVAVSTSA WRWLFYGPAM AAALSFGGLF
MYYYPPAHPR GLPFKQALRA LDFGGALLFT VAATLTLTGI VYSIQLPSSD PKVVGTLVSG
LGMLVVFGLY ETFVPLAQPL TPTRVFTKGR GRDLTAPFVA AFVVTMFYYA INVIWPTMIN
VFFTDAATSF RYQIVLTLPA NLGLCLGAFL LSVLGTRIGH WRWTLTASVT VMVVFGALLA
VVTPERKGLA IALVFIEQMG FGWAQYLSIA FVQFGTDQVE LGIAGGLAGV SRFAGGTVAI
SVFSTILSNV TTKQILKLVP AAAMGAGLPA SSVSALIAAL AQGSAALEAV PGISDAVIAA
ASKAYQQAYV VGLRTTALSS LSFGIVAIIA CLFCNNIDDK MNNKIEIFLE NDVHADKNRF
H
//
