ID   S3CHI5_OPHP1            Unreviewed;       876 AA.
AC   S3CHI5;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Vacuolar transporter chaperone 4 {ECO:0000313|EMBL:EPE05793.1};
GN   ORFNames=F503_08324 {ECO:0000313|EMBL:EPE05793.1};
OS   Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX   NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE05793.1, ECO:0000313|Proteomes:UP000016923};
RN   [1] {ECO:0000313|EMBL:EPE05793.1, ECO:0000313|Proteomes:UP000016923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE05793.1,
RC   ECO:0000313|Proteomes:UP000016923};
RX   PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA   Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA   Robertson G., Birol I., Bohlmann J., Breuil C.;
RT   "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT   a comparison with the bark beetle-associated pine pathogen Grosmannia
RT   clavigera.";
RL   BMC Genomics 14:373-373(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC       {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004128}.
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DR   EMBL; KE148155; EPE05793.1; -; Genomic_DNA.
DR   AlphaFoldDB; S3CHI5; -.
DR   STRING; 1262450.S3CHI5; -.
DR   VEuPathDB; FungiDB:F503_08324; -.
DR   eggNOG; KOG1161; Eukaryota.
DR   eggNOG; KOG4580; Eukaryota.
DR   HOGENOM; CLU_009308_0_0_1; -.
DR   OMA; AGGKQQN; -.
DR   OrthoDB; 11387at2759; -.
DR   Proteomes; UP000016923; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd07751; PolyPPase_VTC4_like; 1.
DR   CDD; cd14480; SPX_VTC2_like; 1.
DR   Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR   InterPro; IPR003807; DUF202.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR018966; VTC_domain.
DR   InterPro; IPR042267; VTC_sf.
DR   PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR   PANTHER; PTHR46140:SF1; VACUOLAR TRANSPORTER CHAPERONE 4; 1.
DR   Pfam; PF02656; DUF202; 1.
DR   Pfam; PF09359; VTC; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT   TRANSMEM        806..831
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        852..868
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          57..236
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   REGION          99..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          585..610
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          647..686
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        652..666
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   876 AA;  98876 MW;  F869745D37D9BBA8 CRC64;
     MLIIEDLKTK KTTWHRSNSN NAVPTVRSIL PGKRRSKNHR RRAHNTPWRA PPGIVVMKFG
     EQLRSSVIRE YEWAYLDYDG LKAKLRVGSG PIIGADTPAA AANGKKGKKD TPTVDTSSAQ
     SVREWTEDDE AGFVAALENE LEKVHQKQQV KAIEIQRMIA VSEREVNDVV NRLRERGTGD
     GPSEEEFMLL EEDLSDIIAD VHDLAKFVQV NYTGFYKIIK KHDKITGWHL KPVFDTRLKA
     KPFYKENYDA SVVGLSKLYD LVRTRGNPVK GDSSAGGGQA NFVRHTTKYW VHPDNVTELK
     LIVLKHLPVL VFNASKEFDQ QDSAITSIYY DNPDSWDLYE GRLKKTEGAE AIRLRWYGGM
     RSETIFVERK THREDWTGEK SVKARFSIKE KNVNAYMRGE LLPTAIFEKA RKEGKKSKQA
     IAEDERLAAE CQYSILRKGY RPVCRSFYNR TAFQLPGDAR VRISLDTELT MVREDNLDGK
     VRSGDNWRRM DIGIDYPFSQ LPAADVERFP YAVLEVKLQT QMGQEPPEWV RQLISSHLVE
     AVPKFSKFIH GTATLFPDRI NLLPFWLPQM DVDIRKPRSH DFGIRRAGHS ATTATSESDD
     EDDIDSDDEG LADSNALVQQ TRSRQAIGGP AGESSSAAAT IAARLPQQGL PANRDTEDQT
     ADANTALNDP YPVYESDDED EEDSEQTHLE EARRVGGWTY YSALVASYAK AAGRGAVTVA
     ESLVPHPRGS EIPQNERQRQ LFGSRDGIQT KQFRAPKGKK IYVPVRVEPK VYFAAERTFL
     GWLEYSIYIG TIAATLLNFG SKPSSISFVV ATVFTMLAVL SLLYSVGIYF YRSRAIRTRR
     ASAKFYDRYG PSVLCGAMFI AIAINFAFEG HARELW
//