ID S3CP31_OPHP1 Unreviewed; 1189 AA.
AC S3CP31;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 03-MAY-2023, entry version 28.
DE SubName: Full=Nonsense-mediated mrna decay factor {ECO:0000313|EMBL:EPE02340.1};
GN ORFNames=F503_06540 {ECO:0000313|EMBL:EPE02340.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE02340.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE02340.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE02340.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KE148181; EPE02340.1; -; Genomic_DNA.
DR AlphaFoldDB; S3CP31; -.
DR STRING; 1262450.S3CP31; -.
DR VEuPathDB; FungiDB:F503_06540; -.
DR eggNOG; KOG2051; Eukaryota.
DR HOGENOM; CLU_002633_1_1_1; -.
DR OMA; DFQHHQI; -.
DR OrthoDB; 276824at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 3.
DR Gene3D; 4.10.80.160; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR039762; Nmd2/UPF2.
DR InterPro; IPR007193; Upf2/Nmd2_C.
DR PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR Pfam; PF02854; MIF4G; 2.
DR Pfam; PF04050; Upf2; 1.
DR SMART; SM00543; MIF4G; 2.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923}.
FT DOMAIN 493..683
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT DOMAIN 698..905
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 226..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..1037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1095
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1149..1189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..454
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 984..1005
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1019..1035
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1082
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1189 AA; 132153 MW; 6C9A72E79203C732 CRC64;
MDRLKKHLFE VNKSLDSSLK KNTAFIRRLR TAISAANLNS FLQEIASLSL SKYLSEIIPA
CYEGLCRLKT PADIEAGVEI VSTLHQRFGP ADFTEYLGWL LGKGMAAPDK SQFKTLSAEA
RERDEKDRIT LQRVLLRIVT ELWLAGVLRT LEDVNRPDDT TKGAAGKAAD VKFRTSPSAK
PGAADPFPLA VLKDLLGHDR EHANLPLLVT FVKTFSVDIL GVSGSPGEGA RKLGDEDGGS
AAPRPANDKP ISNPETAADT EAIGGPFSPD SALAPSSAGS DGDSITPPEL QAKFRNILSR
YFDDVKGHLL RDQKAISAQS RRNAEAYVKS GEVFEDRQSN FEKQVKAQER LVSNAQVIAD
AIGAEMPDLK DGDDAQITTS SSAIGIVKAG DYLRGQGESS GIWEDEEERR FYENLVDLKG
KVPAILLEDG KKKKADSDDQ VGSKKTESPD DPEAGKAPLA DAANANTSTP AATITTTDEQ
STSIINKSVG AQVDTLLLRL PDLTNKEIID QTAIDFCFLN SKASRNRLIK SLTEVPKGRS
DLLPCWSRLV ATLGQYMPDI PKGLVEYLDA EFRSLQRRKE KDFLGQVRLS NIRYLAELTK
FGIVPEHVVF HCLKVSLDDF SRMNIEIISN LLENCGRYLL RNPDTSPRMT SFLETLQRKK
AMQHIGQAER MLIENAVYYV DPPERPAIQQ KERTPMDLFV RKLVYVDLCK RNANKILRQI
QRLHWEEKEV VEILHKVFSR PGKAKYGNIH LLAGLLSALY RHHSSFVIGI VDGMVESITF
GLELNDFRMN QKRLAEAKYL GEFYTYRLLE HPVIFDIMYK ILTLGHGGAP VPGRINPIDL
PDEYFRIRLV STILETTGSY FSKGASGKKL DFFLAFFQFY IFTKNPLPMD IEFIVQDTFA
LIRPQWKLAT DLEEAAKVFQ VAVVKDLEDK AAASGAGKGA SAVSAAGEAE GEQHDGPASD
DESSDDEIGH GDDLAGGDVE VNIIDDELLS DEDGDDDDDE DDDGGRDSDR SGSESEDEEI
VVTREEEQID PEDEADFERE YARMMAESLE SRKFERKPMF DLALPVRPKT TSQGQTNAEP
GPNGHDNGRE DGTPTMAFSL LTKRGNRQQT RTLELPSDSE FAVAMRNQQL AEREEQQRIK
NLVLNLDLQS DEGEVPERAT SYFHNRPDKG GKDRSQRVRK LQLSDVDWT
//
