ID   S3CQC9_GLAL2            Unreviewed;       510 AA.
AC   S3CQC9;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein {ECO:0000259|Pfam:PF02096};
GN   ORFNames=GLAREA_04691 {ECO:0000313|EMBL:EPE27900.1};
OS   Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Helotiaceae; Glarea.
OX   NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE27900.1, ECO:0000313|Proteomes:UP000016922};
RN   [1] {ECO:0000313|EMBL:EPE27900.1, ECO:0000313|Proteomes:UP000016922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX   PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA   Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA   Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT   "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT   the fungus Glarea lozoyensis.";
RL   BMC Genomics 14:339-339(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC       Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC       {ECO:0000256|ARBA:ARBA00009877, ECO:0000256|RuleBase:RU003945}.
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DR   EMBL; KE145369; EPE27900.1; -; Genomic_DNA.
DR   RefSeq; XP_008085259.1; XM_008087068.1.
DR   AlphaFoldDB; S3CQC9; -.
DR   STRING; 1116229.S3CQC9; -.
DR   GeneID; 19463746; -.
DR   KEGG; glz:GLAREA_04691; -.
DR   eggNOG; KOG1239; Eukaryota.
DR   HOGENOM; CLU_029282_5_0_1; -.
DR   OMA; WWASIVG; -.
DR   OrthoDB; 5395681at2759; -.
DR   Proteomes; UP000016922; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   CDD; cd20069; 5TM_Oxa1-like; 1.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR028055; YidC/Oxa/ALB_C.
DR   PANTHER; PTHR12428:SF66; MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L; 1.
DR   PANTHER; PTHR12428; OXA1; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003945};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        313..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        350..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          193..385
FT                   /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02096"
FT   REGION          78..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          397..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..117
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        406..442
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..495
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   510 AA;  56078 MW;  E85FD27BBF25BF85 CRC64;
     MLPNRGVRCS IQHISIGRRR IAGVSGRQFS SVRYDITRGN PILPGRGTFT TSPRAWSSKT
     HGVVLGATAV RFASWGSWTS GPSSATTPPP PATNQTPIQT PSTTPTTFDE TASSATDPLP
     TPPIPEAPFS VDSTGDFVTP LDNLDNFLVN ASSISPDQIG YLQSLGIQYS RFRPTGLMEF
     VVEHIHVYSG TPWWATIALT AVAVRCVFFK VFVNAAENNT RMRAIMPITK PITEKMQAAA
     KARDQQGVMV HRSELQMIHK RAGVSIVKGF LPTLQFFPAM GTFFLLREMC KIPVPGLETG
     GILWFKDLTL QDPYFILPMA AATMLHLVLR KGGEAGNSTM DPSIQKAMMF GLPALSLAFT
     WWFPAAVQLS FAITSTISYG QVVAMANPTF RSFFNMTPVP PQTPTGPGSS SSSVSQSTTS
     TPSVLSQAEL NSRFQGTSTP KKLFNEAKEG FEGTLKLAKE KMSESTEDRE RKRVEDYEAR
     RQKEIAQEKI RRTNQARSKR QSKFSKYTQK
//