ID S3D2B0_GLAL2 Unreviewed; 1449 AA.
AC S3D2B0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Sec7 {ECO:0000313|EMBL:EPE32672.1};
GN ORFNames=GLAREA_07806 {ECO:0000313|EMBL:EPE32672.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE32672.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE32672.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
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DR EMBL; KE145359; EPE32672.1; -; Genomic_DNA.
DR RefSeq; XP_008080684.1; XM_008082493.1.
DR STRING; 1116229.S3D2B0; -.
DR GeneID; 19466858; -.
DR KEGG; glz:GLAREA_07806; -.
DR eggNOG; KOG0929; Eukaryota.
DR HOGENOM; CLU_004694_0_0_1; -.
DR OMA; FVRHNAL; -.
DR OrthoDB; 4248238at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF402; ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 456..632
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 747..876
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 44..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1028..1082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1130..1158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1173..1253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1284..1303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1371..1449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 940..967
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 73..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1082
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1130..1147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1177..1214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1233
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1408..1434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1435..1449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1449 AA; 160412 MW; 0C55AB8401AFC018 CRC64;
MPLMPGLLRR KGPATSASDV NIRRHSFLSP DALIAEDQPV IDGRASEQIP RRPSAADFLT
PTVPGRPTPG RMSAESGRDR LERSISPATQ DESHKHRRFS MLRFRHASDP QLSARAKLHA
AQQTEAPPLP RPPEIITTAP TMDMNVSKPS KKKSRVRLPG RAKSSLDMHP EEPAKIVTKN
EKLEKKERRK TMSESAASGS KSRVTFDEPA RPSTQTGTSP PAYGDDSTST LALPVTRLSE
SSNGSSGDHG VYATTTTTTH TVHTTTTFFR LPRRKKTPAP LFDLSHLPQK GNPPKQSQSL
GRVSASSSRP LGSESAAVLA LRSPSTDDVG TRNGLPSPLP SPSHSAIART TSAFAAPGVP
SLFRKGSAAS SLSSPTRARL GQRGRSSTLS SLRNAPSDDN LPTPTLPASV RTSTSTGRKS
FGDLFGLSHR LRQNSEPPFP RNGGLATPGS STSKNNSIQL PREPAIVLPE RFEDDTPAKY
LVRLEEAVSR GVVASVLSKG TDQFSSSVLR SYMRGFGFFG DPMDMAIRKL LMEVELPKET
QQIDRCLQSF ANRYHECNPG IYASPDQAYF IAFSLLILHT DVFNKNNKYK MQKPDYLKNT
SGEGIFDEIL GCFYDNISYT PFIHVEDDID INGERIIQHK TKKKSIFPRA STDPSKRPSK
EPVDPYTLII DSKLETLRPN LKEVMPLEEH YSYLGTATSL NLQDLQKTFF RTGVLQIVSA
RSRPDAFMNE KTATNPQDAH PGIVDIKITK VGLLWRKDAK KKKTRSPWQE WGAILTGAQL
YFFRNTTWIK SLMQQHEAHN KLGLDGTPVI FKPPLDSFKP DALMSTDDAV ALLDSDYKKH
KNAFIFVRHG GFEETFLADN EEEMNDWLAK LNYAAAFRTS GVRMRGVVGG NYDGQRSRGI
RRLDSQNEST RSVQTPTGEV TISSGRIDTK MAQDILAARR QIMLQKIAEA EEKLSAAQKQ
LDMQLRNARH LQILAPIQAK TREQVVMAAG RMAAQLKWGR MEIWRLRCHK EILSMDLDEE
KNSEILTPKT DYFGETPTSE KSALGRLHSK SSNLKDQRTP RSPTLHSANR PSTANPNTPR
IGSEQVLEDI FQTPSEVTSS PNFHKQQASW ELPPINFDVR QARKLSVSSA VPSTPSLAQT
PSKASLKPPN SAGVARPETP NVDAAEQAVL EQAGLLEEKS PMRRHSSVVP DTEDSKDQTP
TSEKDKEKLD RGKIRRSLHR TLREAHVPSH HRSRKGKDSA SSVGLSEEGN REDVLSRGTG
SFVVHGKKAS VITFGSELQS MSQEERLRLR KQPNRTSSGV ASSSAIEEDF NSALAEPIVF
HQRHDSAATT STATARSFRE LHQKYHDHTS GVLVNASSDG EDSEAALSVL EGRRSPLPPM
DDEEEEYFAR PVSQQQAMFY TPERSNSPAP DFEDEDFSEQ YHDHLDRGSS KASEQYSERL
RTPPTLLSA
//
