ID S3D2T1_GLAL2 Unreviewed; 461 AA.
AC S3D2T1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=FAD/NAD(P)-binding protein {ECO:0000313|EMBL:EPE32135.1};
GN ORFNames=GLAREA_12217 {ECO:0000313|EMBL:EPE32135.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE32135.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE32135.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007992}.
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DR EMBL; KE145360; EPE32135.1; -; Genomic_DNA.
DR RefSeq; XP_008081190.1; XM_008082999.1.
DR AlphaFoldDB; S3D2T1; -.
DR GeneID; 19471258; -.
DR KEGG; glz:GLAREA_12217; -.
DR eggNOG; KOG2614; Eukaryota.
DR HOGENOM; CLU_009665_6_3_1; -.
DR OMA; GQQTVHR; -.
DR OrthoDB; 2684451at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR46720; HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED; 1.
DR PANTHER; PTHR46720:SF3; HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 297..372
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 461 AA; 50277 MW; CB561C0CF099BCAF CRC64;
MSTENSTQKP FTIAIVGGGI GGIALAIALR HQHVPVQVYE AAPEFAEIGA GMAFGPNAIR
SMELIDPAIR KAFNTRATKN GAKEDEATWI NFRCGLGEPD LIAKVQTTDH DKTGLSSVHR
AHFIDELADL LPEEIAHFGK RLVGLATLDS GKMQLAFEDD TTAHADAVVG CDGVRSRVRQ
FLLDTKSPLE DLTFSGKYAY RGLISMGMAK EALGEYLSGN SQMYLGPEGH ILTYPIAHGK
VMNVIAFKNQ DTPWEHESWV VKNQGDAFKR DFEGWGKPVQ SILQLLDSPD QWALFDHQPA
RTYCQGRVAI LGDAAHASTP HQGAGAGQAI EDALILGRLL GDVQTQGASD IPAAFRAYDA
VRRPRSQKVV TTSRAAGLTY AFQGPDGGDV AGIQEELLQR FQWIWEEDME SQLAQATTML
RGERQVAVGT GRGLVWGWAA VWKQVLEDLV SRVLVFIRGS R
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