ID S3D935_OPHP1 Unreviewed; 491 AA.
AC S3D935;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=rRNA methyltransferase 2, mitochondrial {ECO:0000256|ARBA:ARBA00041184};
GN ORFNames=F503_05100 {ECO:0000313|EMBL:EPE10005.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE10005.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE10005.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE10005.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase RlmE family.
CC {ECO:0000256|ARBA:ARBA00009258}.
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DR EMBL; KE148146; EPE10005.1; -; Genomic_DNA.
DR AlphaFoldDB; S3D935; -.
DR STRING; 1262450.S3D935; -.
DR VEuPathDB; FungiDB:F503_05100; -.
DR eggNOG; KOG4589; Eukaryota.
DR HOGENOM; CLU_555602_0_0_1; -.
DR OrthoDB; 2785996at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10920; RIBOSOMAL RNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10920:SF18; RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL; 1.
DR Pfam; PF01728; FtsJ; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EPE10005.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EPE10005.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 105..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 238..479
FT /note="Ribosomal RNA methyltransferase FtsJ"
FT /evidence="ECO:0000259|Pfam:PF01728"
FT REGION 289..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 53180 MW; 7E2A2E929CA7938F CRC64;
MACLVHICDS AVPPSPTGFE KRAKPAREAT PKTCALQLEP LIHWAPHLAD RPVLFQVAAD
YYAVGVYANF VNGVLPTRLE VLGDNTVSGF SIGTSSVESA RSSSVVVGIV VVALAIFILT
RYIYPYSSAS IPTHATVTEK DRPAAGRVPC ATSLNGNRPR SILTTAIDTG GDRTASRLQN
KPMGVPVMYI SLLLHQCHNS RLFIIKYPLA GTAEQGLICA RGQSPGPEEP GRFQATGGSW
SQVAVERTKP NGRVVGIDLI PAQPPRGVST IQGNFLSPAV RELVKELLAQ PPASPKTPAV
SRPKPTEPDD NKGVIFEEPE NDDADQDGAD AVAPATPEAP NDTVAVDRLS YLESERQATA
SAPVHDTKVD IVLSDMSAPW PQTYGFWLNT LSNPYRRMMN TSGNAFRDHA GSMDLCLAAL
EFASDTLRTG GHFVCKFYQG GEDKAFEMRL KKMFTKVVRE KPGSSRSESK ESFFVALKRK
KGVKWDDIKD M
//
