ID S3DKB5_GLAL2 Unreviewed; 287 AA.
AC S3DKB5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=NAD(P)-binding Rossmann-fold containing protein {ECO:0000313|EMBL:EPE26993.1};
GN ORFNames=GLAREA_02907 {ECO:0000313|EMBL:EPE26993.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE26993.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE26993.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- PATHWAY: Alkaloid biosynthesis; ergot alkaloid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005107}.
CC -!- SIMILARITY: Belongs to the fgaFS/easG family.
CC {ECO:0000256|ARBA:ARBA00005372}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE145370; EPE26993.1; -; Genomic_DNA.
DR RefSeq; XP_008086183.1; XM_008087992.1.
DR AlphaFoldDB; S3DKB5; -.
DR STRING; 1116229.S3DKB5; -.
DR GeneID; 19461963; -.
DR KEGG; glz:GLAREA_02907; -.
DR eggNOG; ENOG502RYYU; Eukaryota.
DR HOGENOM; CLU_007383_10_6_1; -.
DR OMA; WFMQNFS; -.
DR OrthoDB; 1605083at2759; -.
DR UniPathway; UPA00327; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0035835; P:indole alkaloid biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR019901; Ergot_alkaloid_biosynthesis.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR008030; NmrA-like.
DR NCBIfam; TIGR03649; ergot_EASG; 1.
DR PANTHER; PTHR43162; -; 1.
DR PANTHER; PTHR43162:SF1; PRESTALK A DIFFERENTIATION PROTEIN A; 1.
DR Pfam; PF05368; NmrA; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Alkaloid metabolism {ECO:0000256|ARBA:ARBA00022589};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 80..219
FT /note="NmrA-like"
FT /evidence="ECO:0000259|Pfam:PF05368"
SQ SEQUENCE 287 AA; 31811 MW; F91F079193391D5A CRC64;
MAILITGGTG KTASRIAKYC LDSKIPFLVA SRKGQSISSE SYPAVDFDWT NSATFRNPFQ
YKFPNGEGID KVYLVGPDTA DPISEMAPFI DLAKEQGVKK FIYFIGSSAE LGGHYVGKVW
KKLAESEIEY TVLRATWLMD NFLSWQHGAT IKNENKIYSA CGDGQIPFIS ANDIARMGFF
LLTDPKPHET NYRVLGPEPL TFDQVAEKLS QGIGRTIQHV KISEQESCER LVNFGMSEYL
SRFLAKIEVG TANGAENFIG NDVEKVTGKA PETFEAWVAD NKGAFEK
//
