ID S3DS19_GLAL2 Unreviewed; 592 AA.
AC S3DS19;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=All-alpha NTP pyrophosphatase {ECO:0000313|EMBL:EPE34751.1};
GN ORFNames=GLAREA_10445 {ECO:0000313|EMBL:EPE34751.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE34751.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE34751.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
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DR EMBL; KE145356; EPE34751.1; -; Genomic_DNA.
DR RefSeq; XP_008078686.1; XM_008080495.1.
DR AlphaFoldDB; S3DS19; -.
DR GeneID; 19469492; -.
DR KEGG; glz:GLAREA_10445; -.
DR eggNOG; ENOG502QRC1; Eukaryota.
DR HOGENOM; CLU_009521_1_0_1; -.
DR OMA; HTTQGYD; -.
DR OrthoDB; 1801108at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0047429; F:nucleoside triphosphate diphosphatase activity; IEA:InterPro.
DR GO; GO:0009143; P:nucleoside triphosphate catabolic process; IEA:InterPro.
DR CDD; cd10439; GIY-YIG_COG3410; 1.
DR CDD; cd11537; NTP-PPase_RS21-C6_like; 1.
DR Gene3D; 1.10.287.1080; MazG-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025984; DCTPP.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR018647; SLFN_3-like_DNA/RNA_helicase.
DR PANTHER; PTHR46523; DCTP PYROPHOSPHATASE 1; 1.
DR PANTHER; PTHR46523:SF1; DCTP PYROPHOSPHATASE 1; 1.
DR Pfam; PF12643; MazG-like; 1.
DR Pfam; PF09848; SLFN-g3_helicase; 1.
DR SUPFAM; SSF101386; all-alpha NTP pyrophosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50164; GIY_YIG; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 110..196
FT /note="GIY-YIG"
FT /evidence="ECO:0000259|PROSITE:PS50164"
SQ SEQUENCE 592 AA; 67172 MW; B12FAABE2F20398A CRC64;
MVSKVVHETL AAFVAERDWA QFHTPENLAK SVAIEAGELL ECFQWCAEAD PKRVREELAD
VLTYCLLLAD RIGADPEQIE AAKSMMKLAR LDFSQTAVTT WKTHDEKHGN WPVVYLLDDG
NGTARANSNT LRDIYIGETL NAANRMHQHL KTPAKQHLKN IRIVIGERFN KSVCLDLESY
LIKMLAGDGS NRVLNRNNGI TDTQYYQREM YREGFRNIFE RLKAEGVFSR SIPEIENSDL
FKLSPSKALT EEQANSVEEI VNGLLTDIER GSKSTIVIQG DPGTGKTVMA IYMIKLLIDI
KTFTSLEDLD SDLRFCNFFT VRNQRLLHDL RIGLVVPQQS LRKSIQIVFK KTPGLEPSMV
MDPFKVGEAE GVFDLLLVDE THRLNQRANQ AGAILNTKFG TITSSLFGSD DKSKTQLDWI
RAKSRHQIFL LDAAQSVRPA DLPTELLSGL VADTRASGRH FQLRTQMRVK AGSDFVSYVR
WILDPHPLSY PRVKQDFGEY DFRSFDNVAH MRDQIFQHNA EVGLSRMVAG FAWPWNSKKD
KNKFDIEIDE TQLRWNSVIA DWISSRKALE EVGSIHTVQG YDLNYVGVII GL
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