ID   S3E2K1_GLAL2            Unreviewed;       596 AA.
AC   S3E2K1;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Zinc/iron permease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GLAREA_07822 {ECO:0000313|EMBL:EPE32688.1};
OS   Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Helotiaceae; Glarea.
OX   NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE32688.1, ECO:0000313|Proteomes:UP000016922};
RN   [1] {ECO:0000313|EMBL:EPE32688.1, ECO:0000313|Proteomes:UP000016922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX   PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA   Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA   Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT   "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT   the fungus Glarea lozoyensis.";
RL   BMC Genomics 14:339-339(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KE145359; EPE32688.1; -; Genomic_DNA.
DR   RefSeq; XP_008080700.1; XM_008082509.1.
DR   AlphaFoldDB; S3E2K1; -.
DR   STRING; 1116229.S3E2K1; -.
DR   GeneID; 19466874; -.
DR   KEGG; glz:GLAREA_07822; -.
DR   eggNOG; KOG2474; Eukaryota.
DR   HOGENOM; CLU_023518_1_0_1; -.
DR   OMA; HVVDCAH; -.
DR   OrthoDB; 1381711at2759; -.
DR   Proteomes; UP000016922; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003689; ZIP.
DR   PANTHER; PTHR11040:SF205; ZINC-REGULATED TRANSPORTER 3; 1.
DR   PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR   Pfam; PF02535; Zip; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        473..495
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        507..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        544..564
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        576..594
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          226..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          291..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          375..423
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..243
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..400
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   596 AA;  64172 MW;  2A5119C72D41CA0B CRC64;
     MATYILRRGG REHCSPQIAK PSLTSKHPPT RLLSSFVLKE LILCLKSYFL LFCRDHPGPS
     RVAAFPISCR VLSQAESRVV AARGNYTKKE RQRLGARQRI AVKMADGIGI WKMDNDTRGW
     IMCTVSGIAC MVGAGIVYID KIIQLFPSKK NFRIQESDTF AAASLSFSFG VMIFIALYSM
     LPSAKTSFIK GGLSTSTAAW AILGGFVCGF VVIQIVSRYI HSHIPSTEKE CEPPSHDFPH
     SFHGSRRSSN GSYESAEPDN TDLKVPRRNG RATESTPLLS EELNGRHPAS AINHLTGTDG
     TSTVKGNNDE TSRRPSMIQL GKTRALSFLK DTKGNCDSKG PCYGFSKACG HHCVSHSTLS
     GANSRRATMP HADTHLDDDL EASTGRLRSA TTTAGSRGQS RDRQSVEEAL DTISESPVGD
     VEAQTHRHST STGHHHEFDN MFMSSGVQSV ISIAVHKFPE GFITYATNHA NPALGWSVFI
     ALSIHSIVEG FIMAMPLHFA FGSKGKAFWT ASIIGGLSQP AGAGIAAAWF KIAGKNGGNP
     SEALYGGMFA VTSGIMASVA ISLFTDSLDH ANNKTLCTGF AFLGIIIMGM AQALTA
//