ID S3EFS2_GLAL2 Unreviewed; 389 AA.
AC S3EFS2;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=HLH, helix-loop-helix DNA-binding protein {ECO:0000313|EMBL:EPE37038.1};
GN ORFNames=GLAREA_09201 {ECO:0000313|EMBL:EPE37038.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE37038.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE37038.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KE145352; EPE37038.1; -; Genomic_DNA.
DR RefSeq; XP_008076353.1; XM_008078162.1.
DR AlphaFoldDB; S3EFS2; -.
DR STRING; 1116229.S3EFS2; -.
DR GeneID; 19468249; -.
DR KEGG; glz:GLAREA_09201; -.
DR eggNOG; KOG2588; Eukaryota.
DR HOGENOM; CLU_709905_0_0_1; -.
DR OMA; FEDWMRW; -.
DR OrthoDB; 1369766at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11399; bHLHzip_scHMS1_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR47336; TRANSCRIPTION FACTOR HMS1-RELATED; 1.
DR PANTHER; PTHR47336:SF2; TRANSCRIPTION FACTOR HMS1-RELATED; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:EPE37038.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 263..335
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 14..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 389 AA; 43683 MW; E8FFAAFE71C36F46 CRC64;
MAIIFRQGAP AIDYYSQSTQ PPQTDSLISP SDIWDSNSHS DSIFTRAESS DSSFASPTEP
EDNIFSSKNY NLPRNNIEVD IKSEEAFNFG SFEDWMRWDD PSDAALSPEL EFMPELKTEP
LSSTLAYPEF SGDSNSRMTI NNREDSVEFG RDALSEEPSF PSSETQNSPG ENLYSTPLSW
SQPLPGTESR VPFGNYLSPQ QEARLRDIAM PPSRTRAVNQ YPGSPSSDDM GMDNLRKRKS
SVDEDDDDDT PLPQSSSSKH PPVKKTAHNM IEKRYRTNLN DKIAALRDSV PSLRVMSRKN
SNGEEIHEDL QGLTPAHKLN KATVLSKATE YIAHLEKRNK YLTRENASLK SRIDAFEILV
MARQQSLNPT NNPMNDSMAG RSRDSGYMM
//
