ID S3K3F1_TREMA Unreviewed; 585 AA.
AC S3K3F1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Xaa-Pro aminopeptidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF9194_01832 {ECO:0000313|EMBL:EPF31486.1};
OS Treponema maltophilum ATCC 51939.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=1125699 {ECO:0000313|EMBL:EPF31486.1, ECO:0000313|Proteomes:UP000014541};
RN [1] {ECO:0000313|EMBL:EPF31486.1, ECO:0000313|Proteomes:UP000014541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51939 {ECO:0000313|EMBL:EPF31486.1,
RC ECO:0000313|Proteomes:UP000014541};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Leonetti C., Blanton J.M.,
RA Dewhirst F.E., Izard J., Walker B., Young S., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Treponema maltophilum ATCC 51939.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPF31486.1}.
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DR EMBL; ATFF01000006; EPF31486.1; -; Genomic_DNA.
DR RefSeq; WP_016526095.1; NZ_KE332518.1.
DR AlphaFoldDB; S3K3F1; -.
DR STRING; 1125699.HMPREF9194_01832; -.
DR PATRIC; fig|1125699.3.peg.1851; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_4_12; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000014541; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014541}.
FT DOMAIN 6..130
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 304..514
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 526..585
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 585 AA; 64974 MW; DD6C6E8EC0714671 CRC64;
MTVPQRLAAL RQKMKEHGFA AYVIPTADPH LCEYVPAHYK TREYISGFTG SAGTVAVTAD
KAGLWTDGRY FLQAEKQLAG SGIELFKMDE KGVPTLNAFL KSVLKPNDKV GIDGKTLSVQ
NYESMKEELD PITIATDADL IGDIWQDRPE ALMSDVFILG EMYTGKSARD KTEQVRSALK
EKGADSTIIG ALEDVCWLFN IRAHDIAYNP VATAYALVTA KQAILFINKK QLNAESEKYL
RAQGVAIMPY EAVFAEAAKL TGTVYMDPAR TNVYLRDKIK ARIIKGLNFT TALKAVKNSV
ELRNIDEAME KDGAAMVKIL RWIEQNASSG ITECDVSEKL LEFRAQGKDF IEASFETIAG
YGSNGAIIHY APHKESCAKL KPKSFLLLDS GGHYLNGTTD ITRTVALGPL TKEEKENYTL
VLKSHIRLAC AKFKAGATGL SLDTIARECL WDRGKDYNHG TGHGVGFVLA VHEGPQSISK
RYINEPLKLG MLTSNEPGLY IENKHGIRIE NLVVTVPFMQ TEHGDFYRFK TVTLCPIDTR
PIVSGILSEE EKAWLNDYHK EVFKRLLPYL DGAHKSFLRE KTAKI
//
