ID S3L347_TREMA Unreviewed; 468 AA.
AC S3L347;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF9194_01542 {ECO:0000313|EMBL:EPF31199.1};
OS Treponema maltophilum ATCC 51939.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=1125699 {ECO:0000313|EMBL:EPF31199.1, ECO:0000313|Proteomes:UP000014541};
RN [1] {ECO:0000313|EMBL:EPF31199.1, ECO:0000313|Proteomes:UP000014541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51939 {ECO:0000313|EMBL:EPF31199.1,
RC ECO:0000313|Proteomes:UP000014541};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Leonetti C., Blanton J.M.,
RA Dewhirst F.E., Izard J., Walker B., Young S., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Treponema maltophilum ATCC 51939.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPF31199.1}.
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DR EMBL; ATFF01000006; EPF31199.1; -; Genomic_DNA.
DR RefSeq; WP_016525810.1; NZ_KE332518.1.
DR AlphaFoldDB; S3L347; -.
DR STRING; 1125699.HMPREF9194_01542; -.
DR PATRIC; fig|1125699.3.peg.1554; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_008392_0_2_12; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000014541; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF15; BETA-HEXOSAMINIDASE LPQI; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000014541}.
FT DOMAIN 66..408
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
SQ SEQUENCE 468 AA; 51752 MW; 709711EC022A7121 CRC64;
MKVGFRRLRR KFFPSFLPPL ILLIFCCGLF LLPICSCSAR ANSDTLKAER DKIEAAFDRL
IGSLSLEEKL CQLFIVSVDG TVSSASAVSY DIPPGGYILF ARNFTGKPEQ IIALTDSTRN
FYAAQHTQKC TEKYAGKGEC LPPFFAIDHE GGEVNRLRGI ASPLPSAEAV ARLLGPEKAE
ELYLYAAYQL AALGIHVNFA PVVETAGEHN AAFLGRRSFG SAEQVEVYAS AFVRAFNKGG
IFCVLKHFPG NSNEDPHRTL PVLEGSEADI RELYVLPFAS LISSLAEVRD FEIPAADPFP
FAGVLMSHAV VPAFDAENPA CFSRAVVTDL LKNELHFDGL IFSDDLYMLD GKLFSVADCV
IKALRSGVHM CMLSRPVYKD IVSELTEKIG NDSELQTITD EALRRILKAK LRMGLLKLEP
TEDGEYALVP AQFNEAEEDA SLRLQNSLEK FRDAKQKGDA LYYEYWSK
//
