ID S3XML3_9ACTN Unreviewed; 517 AA.
AC S3XML3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Succinate CoA transferase {ECO:0000313|EMBL:EPH06583.1};
GN ORFNames=HMPREF1531_00483 {ECO:0000313|EMBL:EPH06583.1};
OS Propionibacterium sp. oral taxon 192 str. F0372.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Propionibacterium.
OX NCBI_TaxID=1203605 {ECO:0000313|EMBL:EPH06583.1, ECO:0000313|Proteomes:UP000014567};
RN [1] {ECO:0000313|EMBL:EPH06583.1, ECO:0000313|Proteomes:UP000014567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0372 {ECO:0000313|EMBL:EPH06583.1,
RC ECO:0000313|Proteomes:UP000014567};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Kirega A., Socransky S.S.,
RA Dewhirst F.E., Izard J., Walker B., Young S., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Propionibacterium sp. oral taxon 192 str. F0372.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPH06583.1}.
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DR EMBL; ATFL01000003; EPH06583.1; -; Genomic_DNA.
DR RefSeq; WP_016668293.1; NZ_KE340297.1.
DR AlphaFoldDB; S3XML3; -.
DR STRING; 1203605.HMPREF1531_00483; -.
DR PATRIC; fig|1203605.3.peg.502; -.
DR eggNOG; COG0427; Bacteria.
DR HOGENOM; CLU_019748_3_0_11; -.
DR OrthoDB; 9801795at2; -.
DR Proteomes; UP000014567; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014567};
KW Transferase {ECO:0000313|EMBL:EPH06583.1}.
FT DOMAIN 9..169
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 332..468
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 293
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 268..272
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 363
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 383
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 387
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 407
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 517 AA; 56374 MW; F7BCD54859B684DD CRC64;
MSERIRHQAF RDKIMTAEEA AALVTPGASI GFSGFTGAGY PKEFPVALAK RLTEAKEKGE
DFRIKIFTGA STAPELDGAL ADTGGVALRV PYQSDPHMRT AINNGTTDYV DTHLSHGPKY
VNMGFFGEMD FAVVEATAIT TEGEIVPSSS VGANRTYLDN AKKVIVEVND WQTEDLYGLH
DIYYGMDITS FRSPIPISQP GAIIGQPTLR VDPSKIIAVI KTSDPDRNSP FKPLDDDSRA
IAAHMLDFLE LEVRAGRMPK NLFPLQSGVG NVANAVLAGL KESKFEHMTS YTEVIQDGMI
DLIDSGKIDV ASATSFSLSP DAAHHMNEHA RDYQGKIIMR PSDVSNHPEV IRRLFVIACN
AMIEADIYGN VNSTHVMGTR MMNGIGGSGD FARNAGYSIF VSPSLAKNGD ISAIVPMVSH
HDHTEHDVMV LITEQGLADL RGLAPRQRAK LIINNCAHPD YRDELMDYYE QGLKVSKGIH
TPHVLDRSLS FHKRFLETGS MKPQASAPQA AEEAASE
//
