ID   S3ZUQ2_9ACTN            Unreviewed;      1216 AA.
AC   S3ZUQ2;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Putative 5-oxoprolinase {ECO:0000313|EMBL:EPH42110.1};
GN   ORFNames=STRAU_4827 {ECO:0000313|EMBL:EPH42110.1};
OS   Streptomyces aurantiacus JA 4570.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX   NCBI_TaxID=1286094 {ECO:0000313|EMBL:EPH42110.1, ECO:0000313|Proteomes:UP000014629};
RN   [1] {ECO:0000313|EMBL:EPH42110.1, ECO:0000313|Proteomes:UP000014629}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JA 4570 {ECO:0000313|EMBL:EPH42110.1,
RC   ECO:0000313|Proteomes:UP000014629};
RA   Gruening B.A., Praeg A., Erxleben A., Guenther S., Mueller M.;
RT   "Draft Genome Sequence of Streptomyces aurantiacus, Which Produces
RT   Setomimycin.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPH42110.1}.
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DR   EMBL; AOPZ01000257; EPH42110.1; -; Genomic_DNA.
DR   RefSeq; WP_016642951.1; NZ_AOPZ01000257.1.
DR   AlphaFoldDB; S3ZUQ2; -.
DR   PATRIC; fig|1286094.4.peg.4773; -.
DR   OrthoDB; 9768323at2; -.
DR   Proteomes; UP000014629; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014629}.
FT   DOMAIN          6..190
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          210..497
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          515..668
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          692..1199
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
FT   REGION          1173..1216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1216 AA;  129562 MW;  F34871C0C115023C CRC64;
     MTGWQFWVDR GGTFTDVVGR RPDGGLLTHK LLSDNPARYA DAAVAGIREL LVQAGALDAG
     TSRGAGDVPI DVVRMGTTVA TNALLERKGE PTALVITRGF RDALRIAYQN RPRIFARDIV
     LPEELYERVI EYDERVGADG EVLRAPDLDG LAEALRKAYD DGIRAVAVVC VHSHLYPAHE
     QAAGDLARRT GFPQVSLSSE ASPLMKLVPR GDTAVVDAYL SPVLRRYVEH VADELQGVRL
     MFMQSNGGLA EAGQFRGKDA ILSGPAGGIV GMARMSRLAG FDRVIGFDMG GTSTDVSHYA
     GAYERVFTTQ IAGVRLRAPM LDIHTVAAGG GSVLHFDGAR YRVGPDSAGA DPGPASYRGG
     GPLTVTDANV ALGRVQAAHF PRVFGPDGDQ PLDDALVRDR FADLAREITE QTGDDRTPEQ
     VAEGYLQIAV ANIAAAVKRI SVQKGHDITR YALTTFGGAG GQHACMAADS LGIRTVLVPP
     MAGVLSALGI GLADTTAMRE QSVEAPLEAP SMPRVHKTAD DLEAAARDQL AAEDVPADRV
     RVTRRAHLRY DGTDTTLSVE LTEPDAMTRA FEEHHRATYS FTLDRPVVVE ALSVEATGLT
     EPPDLSVLGG TTEHGTARTV RLHTGGSWRE VPLHRREELP PGERVTGPAI ITEAGATTVV
     DDGWQGAMTD DGHLVMERVA APASSDAGTE ADPVLLEVFN NLFMSIAEQM GARLESTAQS
     VNIKERLDFS CALFDPDGNL VANAPHIPVH LGSMGTSVKE VIRRRGTTMR PGDAYAVNDP
     YHGGTHLPDV TVITPVFDTS GERILFHVAS RGHHAEIGGI APGSMPARSR TIDEEGILFD
     NWLLVEAGRL REAETLSLLT ETRYPSRNPA TNLADLRAQI AANQKGVDEV GRMIDNFGLD
     VVQAYMRHVQ DNAEDSVRRV IDTLEEGEFT YETDSGAIIQ VRVSVDREQR TATVDFTGTS
     PQLATNFNAP FAVVNAAVLY VFRTLVDDDI PLNDGCLRPL RIVVPAGSFL SPEPPAAVVA
     GNVETSQAIT GALYGALGVQ AEGSGTMNNV TFGNDRHQYY ETVASGSGAG DGFDGASVVQ
     THMTNSRLTD PEVLEWRLPV VLEEFAVRHG SGGEGRWRGG DGAVRRIRFR EPMTVSTLSQ
     HRVVPPYGMA GGEPGALGSG RVERADGAVV RLDGSDSADA GPGDVLVIET PGGGGYGPPP
     HSATGAHTTT DAPRPN
//