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Database: UniProt
Entry: S4D7R6_ENTFL
LinkDB: S4D7R6_ENTFL
Original site: S4D7R6_ENTFL 
ID   S4D7R6_ENTFL            Unreviewed;       710 AA.
AC   S4D7R6;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   10-APR-2019, entry version 26.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=D920_02310 {ECO:0000313|EMBL:EPH95580.1};
OS   Enterococcus faecalis 13-SD-W-01.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1260356 {ECO:0000313|EMBL:EPH95580.1, ECO:0000313|Proteomes:UP000014594};
RN   [1] {ECO:0000313|EMBL:EPH95580.1, ECO:0000313|Proteomes:UP000014594}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13-SD-W-01 {ECO:0000313|EMBL:EPH95580.1,
RC   ECO:0000313|Proteomes:UP000014594};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R.,
RA   Courtney L., Fronick C., O'Laughlin M., Godfrey J., Wilson R.M.,
RA   Miner T., Farmer C., Delehaunty K., Cordes M., Minx P., Tomlinson C.,
RA   Chen J., Wollam A., Pepin K.H., Bhonagiri V., Zhang X., Warren W.,
RA   Mitreva M., Mardis E.R., Wilson R.K.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EPH95580.1}.
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DR   EMBL; ATIO01000129; EPH95580.1; -; Genomic_DNA.
DR   RefSeq; WP_016625073.1; NZ_KE351686.1.
DR   STRING; 1260356.D920_02310; -.
DR   EnsemblBacteria; EPH95580; EPH95580; D920_02310.
DR   PATRIC; fig|1260356.4.peg.2032; -.
DR   OrthoDB; 304844at2; -.
DR   Proteomes; UP000014594; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000014594};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014594};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    278    296       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    336    365       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    385    408       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    420    444       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    450    470       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    509    528       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    610    629       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    641    663       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    669    691       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        1    161       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   710 AA;  79265 MW;  6B9219C4126609FF CRC64;
     MNIALVGNPN SGKTSLFNLL TGSNQYVGNW PGVTVEKKEG LLKKHPDIYI QDLPGIYSLS
     PYTPEEVIAR DYLVHEKPEL IINIIDASNI ERNLYLTTQL LDLGIPMIIG LNMMDVIKKE
     GKKINLEKLS YGLGVPVLPI SALKKQGTEK LIEKMIAASK KSPELPEPCA YDARLEAALH
     EIEDILAEKS SKKRWYAMKY FERDQKAMKE YSASASQEKE IEQLIQLTEK IFEDDSETVL
     VNERYEFITQ LCALCVVSND SFQLSMSDKI DQIATNRWLA LPLFAFVMWL IYYLAIQTVG
     TMGTDWINDT VFGAWIPEKV GHLLAQWQVA DWMQQLILNG IIAGVGAVLG FLPQLIVLFL
     CLSFLEDCGY MARIAFVMDR LFRKFGLSGK SFIPMLIATG CGVPGVMASR TIENEQDRRL
     TIMVTTFMPC SAKLPIIALV AGAFFPHRSW VAPSAYFLGM TAIILSGISL KKTRLFSGDT
     TPFIMELPTY HLPQWSAILR QTYDRSKSFV KKAGTIIFVS SIVIWFSSSY NFVGEAVSED
     QSILAFFGRI SAVLFQPLGW GNWQGTVAAI TGLVAKENII GTFGILFGQS EVSENGREIW
     QTLQQTYTPA AAYALLAFNL LCAPCFAAIG AIHREMNASK WTWIAIGYQC GLAYLVSFIL
     YQFGHLLEGG SIVMSTYLAG LLTIGMIYAL FRKPKRVKTK YPVLSLEGEK
//
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