ID S4MUW7_9ACTN Unreviewed; 670 AA.
AC S4MUW7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Copper transport protein YcnJ {ECO:0008006|Google:ProtNLM};
GN ORFNames=STAFG_5432 {ECO:0000313|EMBL:EPJ37502.1};
OS Streptomyces afghaniensis 772.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1283301 {ECO:0000313|EMBL:EPJ37502.1, ECO:0000313|Proteomes:UP000015001};
RN [1] {ECO:0000313|EMBL:EPJ37502.1, ECO:0000313|Proteomes:UP000015001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=772 {ECO:0000313|EMBL:EPJ37502.1,
RC ECO:0000313|Proteomes:UP000015001};
RA Gruening B.A., Praeg A., Erxleben A., Guenther S., Fiedler H.-P.,
RA Goodfellow M., Mueller M.;
RT "Draft Genome Sequence of Streptomyces afghaniensis, Which Produces
RT Compounds of the Julimycin B-Complex.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPJ37502.1}.
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DR EMBL; AOPY01001495; EPJ37502.1; -; Genomic_DNA.
DR RefSeq; WP_020274313.1; NZ_KE354254.1.
DR AlphaFoldDB; S4MUW7; -.
DR PATRIC; fig|1283301.3.peg.5398; -.
DR HOGENOM; CLU_023176_0_0_11; -.
DR OrthoDB; 5242236at2; -.
DR Proteomes; UP000015001; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR GO; GO:0046688; P:response to copper ion; IEA:InterPro.
DR Gene3D; 2.60.40.1220; -; 1.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR007348; CopC_dom.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF04234; CopC; 1.
DR Pfam; PF05425; CopD; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015001};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..670
FT /note="Copper transport protein YcnJ"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004521644"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..127
FT /note="CopC"
FT /evidence="ECO:0000259|Pfam:PF04234"
FT DOMAIN 342..418
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
FT REGION 414..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..497
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 69147 MW; 4BEA982FEFC79D0F CRC64;
MTQTIAPRVR TMVLLLLAAA CALLAGAGPA SAHAAVTGSD PAQGAVVDKA PARISLTFSE
QVAMSGDSLR VLDPEGKRVD AGEPSNVSGT TYAVRLHSGL PDGTYTVAYQ VVSADSHPVA
GAYTFSIGAP SKTSVSVSGQ STDDGVVGWL YGFGRYVSYA GFIVMAGGAA FVLACWPRGS
GVRPVQRFVV SGWLALTAAT LALLLLRGSF TGSGKVADVF DLSLLGQVLE TKTGAALVSR
LLLLAAAALF IAVLFGAYDK REDAQEKRDL TFGLAIGGVV VAAGLAASWA MSEHASVGLQ
AGIAMPVDVL HLLAVAAWLG GLGALLVALY RAPADAPVDA SAVRRFSRVA FGSVLALIAT
GTYQSWRQLG SWTAFTDTRY GQLLLAKIAL VAVLVGVAWI SRRWTGRLAE TVPAPAEREK
ARVGAGAAAS GEAGADASGV TAGDAEPDGT GDDRTGTDTE AGADTGDQPD AEPADTERAA
QLARQRAARD AARQKRLRDA DPNRFGLRRS VLAEAGIAVV LLAVTTVLTQ TEPGRTEQEA
KAATPSSAST SPDTGASGAL TLNMPFDTGG KDGKGIVTVD LDPARVGDNE MHIYVERPNG
RAFDIPEVKV DFTLKAKDIG PLPVVPDHIA TGHWSANGVQ IPMAGDWKVD VTVRTSDIDE
VTVSKNAQIG
//
