ID   S4MVM2_9ACTN            Unreviewed;       350 AA.
AC   S4MVM2;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Putative DNA polymerase'-5' exonuclease PolX {ECO:0000313|EMBL:EPJ39805.1};
GN   ORFNames=STAFG_3157 {ECO:0000313|EMBL:EPJ39805.1};
OS   Streptomyces afghaniensis 772.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1283301 {ECO:0000313|EMBL:EPJ39805.1, ECO:0000313|Proteomes:UP000015001};
RN   [1] {ECO:0000313|EMBL:EPJ39805.1, ECO:0000313|Proteomes:UP000015001}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=772 {ECO:0000313|EMBL:EPJ39805.1,
RC   ECO:0000313|Proteomes:UP000015001};
RA   Gruening B.A., Praeg A., Erxleben A., Guenther S., Fiedler H.-P.,
RA   Goodfellow M., Mueller M.;
RT   "Draft Genome Sequence of Streptomyces afghaniensis, Which Produces
RT   Compounds of the Julimycin B-Complex.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPJ39805.1}.
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DR   EMBL; AOPY01001405; EPJ39805.1; -; Genomic_DNA.
DR   AlphaFoldDB; S4MVM2; -.
DR   PATRIC; fig|1283301.3.peg.3129; -.
DR   HOGENOM; CLU_069822_0_0_11; -.
DR   Proteomes; UP000015001; Unassembled WGS sequence.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   CDD; cd07436; PHP_PolX; 1.
DR   Gene3D; 1.10.150.110; DNA polymerase beta, N-terminal domain-like; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR010996; DNA_pol_b-like_N.
DR   InterPro; IPR027421; DNA_pol_lamdba_lyase_dom_sf.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   InterPro; IPR047967; PolX_PHP.
DR   InterPro; IPR017078; UCP036978_PHPhdr.
DR   PANTHER; PTHR36928; PHOSPHATASE YCDX-RELATED; 1.
DR   PANTHER; PTHR36928:SF1; PHOSPHATASE YCDX-RELATED; 1.
DR   Pfam; PF14716; HHH_8; 1.
DR   Pfam; PF02811; PHP; 1.
DR   PIRSF; PIRSF036978; UCP036978_PHPhdr; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF47802; DNA polymerase beta, N-terminal domain-like; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   Exonuclease {ECO:0000313|EMBL:EPJ39805.1};
KW   Hydrolase {ECO:0000313|EMBL:EPJ39805.1};
KW   Nuclease {ECO:0000313|EMBL:EPJ39805.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015001}.
FT   DOMAIN          106..185
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   350 AA;  38406 MW;  DE4E63D98A873FBF CRC64;
     MEVAMDPVEA LDRIAFLLER SLAPTYRVRA FRTASRVLKE LGADEVRRRA DAGSLESLKG
     VGPKTAQVVR EALAGEVPGY LRKLEGEAKE PPAVRGGERL RALLRGDCHL HSDWSDGGSP
     IEEMGRAAAA LGHEWAALTD HSPRLTVARG LSAERLREQL DVVAELNETW APFRLLTGIE
     CDILEDGSLD QEPELLDRLD VVVVSVHSKL RMDARSMTRR MVAAVRDPHS DVLGHCTGRL
     LTGRGRPESE FDADEVFAAL AETGTALEIN SRPERLDPPR RLLRRAVDAG VLFSVDTDAH
     APGQLDWQIN GCARAEECGV PSERVVTTWS LEELLAWTRE RRVPSGVTGG
//