ID   S4N0K0_9ACTN            Unreviewed;       595 AA.
AC   S4N0K0;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Putative Cholesterol oxidase {ECO:0000313|EMBL:EPJ39932.1};
GN   ORFNames=STAFG_3025 {ECO:0000313|EMBL:EPJ39932.1};
OS   Streptomyces afghaniensis 772.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1283301 {ECO:0000313|EMBL:EPJ39932.1, ECO:0000313|Proteomes:UP000015001};
RN   [1] {ECO:0000313|EMBL:EPJ39932.1, ECO:0000313|Proteomes:UP000015001}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=772 {ECO:0000313|EMBL:EPJ39932.1,
RC   ECO:0000313|Proteomes:UP000015001};
RA   Gruening B.A., Praeg A., Erxleben A., Guenther S., Fiedler H.-P.,
RA   Goodfellow M., Mueller M.;
RT   "Draft Genome Sequence of Streptomyces afghaniensis, Which Produces
RT   Compounds of the Julimycin B-Complex.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPJ39932.1}.
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DR   EMBL; AOPY01001397; EPJ39932.1; -; Genomic_DNA.
DR   RefSeq; WP_020271981.1; NZ_KE354147.1.
DR   AlphaFoldDB; S4N0K0; -.
DR   PATRIC; fig|1283301.3.peg.2996; -.
DR   HOGENOM; CLU_002483_2_0_11; -.
DR   OrthoDB; 517968at2; -.
DR   Proteomes; UP000015001; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR   PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000015001}.
FT   DOMAIN          199..288
FT                   /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00732"
FT   DOMAIN          483..540
FT                   /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05199"
FT   REGION          543..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   595 AA;  63594 MW;  560E85039A81552C CRC64;
     MPQDTYDYDV IVVGSGFGGS VTALRLTEKG YRVGVLEAGR RFTRETLPKN SWDLKNYLWA
     PKLGMYGIQR IHLLGNVMVL AGAGVGGGSL NYANTLYVPP EPFFEDPQWR DITDWQEELK
     PYYDQARRML GVRLNPTMTP SDVHLKAAAE RMGCGDSFHL APVGVFFGDG EDADGTAKAK
     PGQEVPDPYF GGAGPARRAC AECGECMTGC RHGAKNTLNE NYLYLAEKAG AVVHPLTTVV
     SVTDDSRGGY AVATLPTDDR RKAGGRTYRA RQVVLAAGTY GTQTLLHRMK AGGQLPHLSD
     RLGGLTRTNS EALVGAQTDD RRYRKAHGAP KADFTRGVAI TSSIHPDENT HIEPVRYGKG
     SNSMGSLSIL QVPYAGSGSG TSRVLGFLAH AAKHPLLVLR SLSNRRWSER TIIGLVMQSL
     DNSLTTYLKP SGVGRGLLTA RQGHGAPNPK QIKAATESAS ALAAEINGFA GSNVGELMGT
     PLTAHFLGGC PIGDSRETGV IDPYHRLYGH PGISVVDGAA VSANLGVNPS LTITAQAERA
     MSFWPNKGEP DPRPRQGAAY ERLQPVEPKS PAVPAEAFGA LRLPFLGLPA MPPKS
//