ID   S4R4G9_PETMA            Unreviewed;       399 AA.
AC   S4R4G9;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMAP00000000098.1};
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000000098.1, ECO:0000313|Proteomes:UP000245300};
RN   [1] {ECO:0000313|Ensembl:ENSPMAP00000000098.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase C14A family.
CC       {ECO:0000256|ARBA:ARBA00010134}.
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DR   AlphaFoldDB; S4R4G9; -.
DR   STRING; 7757.ENSPMAP00000000098; -.
DR   Ensembl; ENSPMAT00000000098.1; ENSPMAP00000000098.1; ENSPMAG00000000084.1.
DR   GeneTree; ENSGT00940000164225; -.
DR   HOGENOM; CLU_036904_4_2_1; -.
DR   OMA; NCFRSIH; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001875; DED_dom.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   InterPro; IPR001309; Pept_C14_p20.
DR   InterPro; IPR015917; Pept_C14A.
DR   PANTHER; PTHR48169:SF3; CASP8 AND FADD-LIKE APOPTOSIS REGULATOR A-RELATED; 1.
DR   PANTHER; PTHR48169; DED DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01335; DED; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   PRINTS; PR00376; IL1BCENZYME.
DR   SMART; SM00115; CASc; 1.
DR   SMART; SM00031; DED; 1.
DR   SUPFAM; SSF52129; Caspase-like; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50208; CASPASE_P20; 1.
DR   PROSITE; PS50168; DED; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          2..49
FT                   /note="DED"
FT                   /evidence="ECO:0000259|PROSITE:PS50168"
FT   DOMAIN          98..176
FT                   /note="DED"
FT                   /evidence="ECO:0000259|PROSITE:PS50168"
FT   DOMAIN          183..271
FT                   /note="Caspase family p20"
FT                   /evidence="ECO:0000259|PROSITE:PS50208"
SQ   SEQUENCE   399 AA;  44837 MW;  EEAFF397E74D5CEB CRC64;
     MSHRLELQRL SEQLSEEEVS SLRFLCRDEL PTWASLPTAE LLMALFQAFH PMLTILGISQ
     VDPALFKISI LIPMCEQILT KKVHILGLNT TRDGTVAACR EFLVELNEGI SNDELSSIKY
     CLQDDLPQNR LNNVNSLLEL CHLLEEQGQL SSDNLSMLEQ CFEIAERHDL KKKLNRFKLK
     SPADNIRTAF SNLGFEIMIF HDLSSMDLRN LQSFCPFKKM HSCFVCFVLG KGTDSDINGT
     DGIPVSIEML SMNFNGQHCP ALVGKPKLFF ILTVMVAGTL YGQSLQVDSS GGVHYDDYLE
     ADGPGIPINA DVLECKHVVE EEACSRKDKS DGTPFIKHLT KCLSELWPMG HDLLEVLTEV
     NRRVSVCNQG LQQRPPKLSN TMRKRLILPQ TQGSLKQIS
//