ID S4R9A3_PETMA Unreviewed; 352 AA.
AC S4R9A3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Tripartite motif-containing protein 54 {ECO:0000256|ARBA:ARBA00014725};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000001784.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000001784.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May bind and stabilize microtubules during myotubes
CC formation. {ECO:0000256|ARBA:ARBA00003888}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril, sarcomere, Z line
CC {ECO:0000256|ARBA:ARBA00004216}.
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DR AlphaFoldDB; S4R9A3; -.
DR STRING; 7757.ENSPMAP00000001784; -.
DR Ensembl; ENSPMAT00000001793.1; ENSPMAP00000001784.1; ENSPMAG00000001617.1.
DR GeneTree; ENSGT00940000156529; -.
DR HOGENOM; CLU_013137_5_1_1; -.
DR OMA; LMTEVYY; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19833; Bbox2_MuRF3_C-II; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR033492; Trim54_Bbox2_Zfn.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF32; TRIPARTITE MOTIF CONTAINING 55; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 22..46
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 115..157
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 265..323
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT REGION 318..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..352
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 39679 MW; 4E9D14B305A364C0 CRC64;
MEYSSLLKPT ENLENLERQL MCPICLEVFS KPVVILPCQH NLCRKCANDV FQAANPFMVT
RGNTVTSGGR FRGPLKTHRV IIDFFNTTNI QQLSRVNSAL CLSRAVENHR PVKKVDHPMC
VEHAEEKINI FCLTCSMPTC SLCKVFGAHK DCQVAPLGSV YKSHKNDLSD SISRLVASND
RVQLMISEME HSCKVIDENS RVQKQMLCEQ FDGVYAALEE RKQEMLMVIS QEQEDKNQHV
RDLIKQYNEH LQSASKLVET AFQAMEEPEA AAFLQSASAL QKSVVDATKG SDMPKMEMGY
ENMNHFLVDL DNVQEAVRGI DFGKDAEDED EEEDEEGEEV AESEEGNSDS SD
//
