ID S4RCN6_PETMA Unreviewed; 556 AA.
AC S4RCN6;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Oncoprotein induced transcript 3 {ECO:0000313|Ensembl:ENSPMAP00000002968.1};
GN Name=OIT3 {ECO:0000313|Ensembl:ENSPMAP00000002968.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000002968.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000002968.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
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DR AlphaFoldDB; S4RCN6; -.
DR STRING; 7757.ENSPMAP00000002968; -.
DR Ensembl; ENSPMAT00000002982.1; ENSPMAP00000002968.1; ENSPMAG00000002713.1.
DR GeneTree; ENSGT00940000157851; -.
DR HOGENOM; CLU_037129_2_0_1; -.
DR OMA; GPQSQML; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR Gene3D; 2.60.40.3210; Zona pellucida, ZP-N domain; 1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR048290; ZP_chr.
DR InterPro; IPR001507; ZP_dom.
DR InterPro; IPR017977; ZP_dom_CS.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR PANTHER; PTHR14002:SF18; ONCOPROTEIN-INDUCED TRANSCRIPT 3 PROTEIN; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF00100; Zona_pellucida; 1.
DR PRINTS; PR00023; ZPELLUCIDA.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS00682; ZP_1; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor {ECO:0000256|ARBA:ARBA00022622};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 272..523
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 556 AA; 60630 MW; D5F7C2E60146D375 CRC64;
TPSSPLHTCN LPTRDDRVLY ADLDPCTSYI SLSEEWRNTE FAINGSNGKP ACDRDMAGEW
YRFTGLAGDV MPTFCVDENH CGTHAPVWLN GTHPRLLDGV VSVPACAAFR DNCCMWQSTV
DVKACSGGYY VYRLPRPPVC YHVYCGHFYE PCERDSSSCQ GEDCAQPPSC RCGHGMLLAE
DGNTCMDVNE CEEANGGCAE VCVNLRASFR CECPVGQVLS PDGRSCLEMT LCETNNGGCS
HLCVAAESSH HCECPRGLLL AEDNRTCQVP VRCSPDAIDV AVPKDQVRGL ELFLANASCK
GVSNGTHVNV HFGLKTCGTT LEVTADKIIA SNVLTGIPKQ GPGSNGDLII RTSKLLIQVF
CEFPRHELLS QGFLPKPGNP IPRLWGHSQG HFPFALLLYR EPSFEAPVGP GEMPLAVKLH
QPLYFGLAPT TRLDGLEVLV ERCYATPGQN GNHLVKYFLI RDGCLVDNTI RLLPSSNLLS
KHYQVQVFKF LGKENMEVFL HCEVTVCQAF DAASRCSQGC MRRVRRSAQG GGARPRLAGP
RIPVITGGPI VMHSST
//
