ID S4REI8_PETMA Unreviewed; 590 AA.
AC S4REI8;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor {ECO:0000313|Ensembl:ENSPMAP00000003620.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000003620.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000003620.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat TAF5 family.
CC {ECO:0000256|ARBA:ARBA00009435}.
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DR AlphaFoldDB; S4REI8; -.
DR STRING; 7757.ENSPMAP00000003620; -.
DR Ensembl; ENSPMAT00000003635.1; ENSPMAP00000003620.1; ENSPMAG00000003317.1.
DR GeneTree; ENSGT00940000153342; -.
DR HOGENOM; CLU_005884_3_0_1; -.
DR OMA; RTEHVQM; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.40.500; TFIID subunit TAF5, NTD2 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR007582; TFIID_NTD2.
DR InterPro; IPR037264; TFIID_NTD2_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19879:SF6; TAF5-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L; 1.
DR PANTHER; PTHR19879; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR Pfam; PF04494; TFIID_NTD2; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF160897; Taf5 N-terminal domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 66..196
FT /note="TFIID subunit TAF5 NTD2"
FT /evidence="ECO:0000259|Pfam:PF04494"
FT REPEAT 339..380
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 381..412
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 423..464
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 465..506
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 507..541
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 540..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 62755 MW; B6B32CBE9D62A598 CRC64;
MKRVRSEQLQ SAVNQLLKRR HYTESELAQR QSFRGSQSAE EMAASMAAQL ESGPMNAVSF
GVYEPNPSHY DRQFNALRQF VNAELRGEER VELQTLMSAL SLALCVELAL GGWRSAAEAF
HGRHVGPVAH THEQRLLAER LGAALSRQDV GSDTCVRTLT EHKLCVELGV VAHGRLMRHL
LQGEHGLLLR AVSTHLRLDV RAQARSSAAG LELYSDGTGG SGGGGASARK MNALPPDEVS
LELLQDSIRR VREGPLNAAT VCLYGFKSVP APPCAAEVAP GMGMLAAGYE DSRVMLWSLG
PRKLRTARHN VDVARINLAC DILDDKVVED SKGSDVKTLR AHSGPVYAVR FLPGGAGLLS
CSEDASVRFW DPRTFTNTAV YQGHAYPVWD VDVSALGLYF CSGSHDRTAR LWVPERAFPL
RVYAGHVSDV NVVRFHPNGS YVATGSADRT VRLWSAQQGS AARLFTGHRG AVLALAFSPG
GRLLASGGED QRVRLWDIGS GAIVKELRGH SDDITCLSFS PDGSALASGS SDGSVRVWDV
RGASTNPGGG GGGSGTGGGG TGGGGGTLNV QFMASNLLLV SAVTRDEPAG
//
