ID   S4RGB6_PETMA            Unreviewed;       554 AA.
AC   S4RGB6;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Glycoprotein nmb {ECO:0000313|Ensembl:ENSPMAP00000004248.1};
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000004248.1, ECO:0000313|Proteomes:UP000245300};
RN   [1] {ECO:0000313|Ensembl:ENSPMAP00000004248.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; S4RGB6; -.
DR   STRING; 7757.ENSPMAP00000004248; -.
DR   Ensembl; ENSPMAT00000004265.1; ENSPMAP00000004248.1; ENSPMAG00000003879.1.
DR   GeneTree; ENSGT00950000183188; -.
DR   HOGENOM; CLU_017264_0_0_1; -.
DR   OMA; HGWRKWN; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00146; PKD; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR045219; PKAT.
DR   InterPro; IPR046846; PKAT_KLD.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   PANTHER; PTHR11861:SF8; -; 1.
DR   PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR   Pfam; PF20433; PKAT_KLD; 1.
DR   Pfam; PF00801; PKD; 1.
DR   SUPFAM; SSF49299; PKD domain; 1.
DR   PROSITE; PS50093; PKD; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        486..507
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          223..261
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   REGION          72..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        343..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   554 AA;  59631 MW;  8E6B5EA43FB3173F CRC64;
     GWMSTDSSYW DEDRYPIRSD NGRDRHRCWP MRNVTVNVTN DGPTLVGSKL TVSVTIISPW
     HGANGTASWN HTYDDNYTEG EEDHGEENWS HDDQQSNTFP NGKPFHRDRH RQRYLPRLYV
     YIWSTEGKYY TMVNGNSSNV TIDTTDIPVG THNISLLLYR GGQSAKQLCA IANVTDNYTV
     TDSVPLSVKI SQMGDRNSSD LIFLENAPVS FTATPHDPSG YLGNATLTYA WNFGDGTEVV
     VGPNASVNHT YSAIGSFSMS LWLRAVIPTP CGSLPFSLPL SSTPISTTSL SPSLPPLSTP
     SLSPYFEPLS LHTTEHNTRG ALSFSAINPT GQPGGAGATV PDGADLQQSS TKSPPTPSPT
     CQLVRYGSFT ANVTIVEGIS SVAVVALMPS VVTMQGGGAV DFMVTCSGSL PSEVCTVVSD
     EACVWPVSGS CRPLVLAAGD PCSLTLREQF NGSGIFCLNV SLADAVSLAV VSTHVDFNAE
     STSAKFLGPA VFFAGIVPLV LLGLLFYKKY RQYTPVAPPG MELSHGPGTL DWVKFIRNKS
     GEKNPLLNAQ KQPI
//