ID   S4RL93_PETMA            Unreviewed;       134 AA.
AC   S4RL93;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=E2F/DP family winged-helix DNA-binding domain-containing protein {ECO:0000259|SMART:SM01372};
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000005979.1, ECO:0000313|Proteomes:UP000245300};
RN   [1] {ECO:0000313|Ensembl:ENSPMAP00000005979.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC   -!- SIMILARITY: Belongs to the E2F/DP family.
CC       {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
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DR   AlphaFoldDB; S4RL93; -.
DR   STRING; 7757.ENSPMAP00000005979; -.
DR   Ensembl; ENSPMAT00000006007.1; ENSPMAP00000005979.1; ENSPMAG00000005432.1.
DR   GeneTree; ENSGT00940000157909; -.
DR   HOGENOM; CLU_137012_0_0_1; -.
DR   OMA; QEYGRTF; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.20.140.80; Transcription factor DP; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR037241; E2F-DP_heterodim.
DR   InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR   InterPro; IPR038168; TF_DP_C_sf.
DR   InterPro; IPR014889; Transc_factor_DP_C.
DR   InterPro; IPR015648; Transcrpt_fac_DP.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12548; TRANSCRIPTION FACTOR DP; 1.
DR   PANTHER; PTHR12548:SF9; TRANSCRIPTION FACTOR DP; 1.
DR   Pfam; PF08781; DP; 1.
DR   Pfam; PF02319; E2F_TDP; 1.
DR   SMART; SM01372; E2F_TDP; 1.
DR   SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU003796};
KW   Nucleus {ECO:0000256|RuleBase:RU003796};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW   Transcription {ECO:0000256|RuleBase:RU003796};
KW   Transcription regulation {ECO:0000256|RuleBase:RU003796}.
FT   DOMAIN          8..95
FT                   /note="E2F/DP family winged-helix DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM01372"
SQ   SEQUENCE   134 AA;  15530 MW;  D9DC7DC30A61BFA6 CRC64;
     RKSRKGDKRG KGLRHFSMRV CEKVRAKGTT TYNEVADELV AEFSSTLRAS QEVCGCVCTQ
     TYDQKNIRRR VYDALNVLMA MNIISKERKE IRWIGLPTNS AQECHNLETE KQRRLERIKQ
     KQAHLHELIL QVGA
//