ID S4RLM1_PETMA Unreviewed; 306 AA.
AC S4RLM1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=General transcription factor IIE, polypeptide 1, alpha {ECO:0000313|Ensembl:ENSPMAP00000006107.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000006107.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000006107.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TFIIE alpha subunit family.
CC {ECO:0000256|ARBA:ARBA00008947}.
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DR AlphaFoldDB; S4RLM1; -.
DR Ensembl; ENSPMAT00000006136.1; ENSPMAP00000006107.1; ENSPMAG00000005549.1.
DR GeneTree; ENSGT00390000016696; -.
DR HOGENOM; CLU_051021_1_0_1; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039997; TFE.
DR InterPro; IPR017919; TFIIE/TFIIEa_HTH.
DR InterPro; IPR002853; TFIIE_asu.
DR InterPro; IPR024550; TFIIEa/SarR/Rpc3_HTH_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13097:SF7; GENERAL TRANSCRIPTION FACTOR IIE, POLYPEPTIDE 1, ALPHA; 1.
DR PANTHER; PTHR13097; TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT; 1.
DR Pfam; PF02002; TFIIE_alpha; 1.
DR SMART; SM00531; TFIIE; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51344; HTH_TFE_IIE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..104
FT /note="HTH TFE/IIEalpha-type"
FT /evidence="ECO:0000259|PROSITE:PS51344"
FT REGION 260..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 306 AA; 34657 MW; A8B111369E514299 CRC64;
MTEPDVLTEV PASLKRLAKF IVRGFYGSEY ALALDVLIRN PCVREEDIQE LLKFDRKQLR
SVLNTLKADK FIKCRMCMET APDGKSTRHN YYFINYRLLV NVVKYKLDHM RRKLETDERD
STNRASFRCP DCSKTFTDLE ANQLYDLASG LFMCTFCRRE VEEDESAVPK KDARTLVARF
NEQIEPIYAL LRETEDINLS HDVLEPEPSD IPALKHLRGH SHTLRGQAVG AGVVPAREAW
SARAPTYDDL YTQNVTISLE QGDPERRGGS SSASATAAAA AAASEDRRPA KERPVWMTES
TVQGAY
//
