ID   S4RRI1_PETMA            Unreviewed;       267 AA.
AC   S4RRI1;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Neuralized E3 ubiquitin protein ligase 2 {ECO:0000313|Ensembl:ENSPMAP00000007817.1};
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000007817.1, ECO:0000313|Proteomes:UP000245300};
RN   [1] {ECO:0000313|Ensembl:ENSPMAP00000007817.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; S4RRI1; -.
DR   STRING; 7757.ENSPMAP00000007817; -.
DR   Ensembl; ENSPMAT00000007852.1; ENSPMAP00000007817.1; ENSPMAG00000007090.1.
DR   GeneTree; ENSGT00940000159689; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.60.120.920; -; 1.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR037962; Neuralized.
DR   InterPro; IPR006573; NHR_dom.
DR   InterPro; IPR001496; SOCS_box.
DR   InterPro; IPR036036; SOCS_box-like_dom_sf.
DR   PANTHER; PTHR12429; NEURALIZED; 1.
DR   PANTHER; PTHR12429:SF8; NEURALIZED-LIKE PROTEIN 2; 1.
DR   Pfam; PF07177; Neuralized; 1.
DR   Pfam; PF07525; SOCS_box; 1.
DR   SMART; SM00588; NEUZ; 1.
DR   SMART; SM00969; SOCS_box; 1.
DR   SUPFAM; SSF158235; SOCS box-like; 1.
DR   PROSITE; PS51065; NHR; 1.
DR   PROSITE; PS50225; SOCS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245300}.
FT   DOMAIN          2..226
FT                   /note="NHR"
FT                   /evidence="ECO:0000259|PROSITE:PS51065"
FT   DOMAIN          230..267
FT                   /note="SOCS box"
FT                   /evidence="ECO:0000259|PROSITE:PS50225"
SQ   SEQUENCE   267 AA;  29652 MW;  7A25A9A1AFEFA259 CRC64;
     AYEKFHVVHG GNMHMDSTRT HATRVRSFGD AVCMSAQPLP PGRVFLVELS QKETGWCGHL
     RVGLTRLCPG GSDGLSRQRQ PKIVVFGKSW VKYELKNHLT KAIGTACSMP CCGHALRGAH
     VTTFTVDVWL YVGNHVIVRD SLVGRSRVGR YSHLLDPLFK THILSTTARG TRIGVIWRIL
     EEEGVMHLLV NGRDLGVFAR GIPTHTPIFA VVDVFGCTRA VTVLHVEYAV PSLQTICRRM
     IQKLTVNRLA ISRLGLPAAL QCYCQYK
//