ID   S4RW11_PETMA            Unreviewed;       658 AA.
AC   S4RW11;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=A kinase-anchoring proteins AKAP-5 and AKAP-12 calmodulin (CaM)-binding domain-containing protein {ECO:0000259|PROSITE:PS51893};
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000009401.1, ECO:0000313|Proteomes:UP000245300};
RN   [1] {ECO:0000313|Ensembl:ENSPMAP00000009401.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; S4RW11; -.
DR   STRING; 7757.ENSPMAP00000009401; -.
DR   Ensembl; ENSPMAT00000009441.1; ENSPMAP00000009401.1; ENSPMAG00000008542.1.
DR   GeneTree; ENSGT00730000111244; -.
DR   HOGENOM; CLU_417145_0_0_1; -.
DR   OMA; NWEALIC; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR   GO; GO:0051018; F:protein kinase A binding; IEA:InterPro.
DR   GO; GO:0010739; P:positive regulation of protein kinase A signaling; IEA:InterPro.
DR   GO; GO:0090036; P:regulation of protein kinase C signaling; IEA:InterPro.
DR   InterPro; IPR028540; AKAP12.
DR   InterPro; IPR001573; AKAP_WSK.
DR   PANTHER; PTHR23209; A-KINASE ANCHOR PROTEIN 12; 1.
DR   PANTHER; PTHR23209:SF4; A-KINASE ANCHOR PROTEIN 12; 1.
DR   Pfam; PF03832; WSK; 1.
DR   PROSITE; PS51893; AKAP_CAM_BD; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245300}.
FT   DOMAIN          487..507
FT                   /note="A kinase-anchoring proteins AKAP-5 and AKAP-12
FT                   calmodulin (CaM)-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51893"
FT   DOMAIN          639..658
FT                   /note="A kinase-anchoring proteins AKAP-5 and AKAP-12
FT                   calmodulin (CaM)-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51893"
FT   REGION          1..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          83..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          204..244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          338..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..66
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..169
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        204..219
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..381
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        410..438
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        439..469
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        475..489
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..518
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        519..536
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        539..560
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        574..600
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..628
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   658 AA;  70437 MW;  5E64272B3FA240B4 CRC64;
     VGQGDTAAMA ETDSAAPEQA AMAEVPPGQT NETEKVNGDS DAPPAAQEGE VTQAAEQTTS
     SSAAPQRDLG FKKVFKLGGF KFTLKKDREE PPESVTLLTV KDTDGEGNGD FNGKVEEAQS
     KQQVVENGAD VAAVKDPEQK SGEEAAASSI ENDADDQKGV HENGTKESAE EAVASESPVG
     GFTAHVTTPL RKMFNNRLFA GLRRKSSKAE KDDKNHQLGN EPLVESTPEP VIPEPAVEEK
     SADATKESVL AAIDKVTEAL QKQTTDINDV EVAQEEAAVA ILKSEQSVEQ SASVLEEKAE
     MCSQEIKLNE APKQENVNGE QVECSATIAE NSHPIAQEAG VVEISAPSAT SELTQDKVDT
     RTDPNVSPDG LTAQTSKTEE TEQDLTSPDK SKTPSSPLKK FFMGGPLKKL SLKRGKEKEK
     SEGKAQTEVN EQKPDETEAT TSHAYNQTAS PSGIEIDSQV PQSPTQPEAA DPSEEAEVVA
     EKKRDGITPW SSFKKLVKPR RRTKNNSESD KEEEPGEAGK TTTMSSTTSG VSGGKEASLN
     SEVDEHIKED GGKKKTEHLG PNWEALICIG SSKKRGRKSS DSDSSLQDLQ KQKDEAPAQG
     DSKPESSATT VANKEELPEK DEVQSEQPKA EVAEAPKNTV NWGSLKRLVT PKKRNKSK
//