ID S4RX45_PETMA Unreviewed; 253 AA.
AC S4RX45;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000009785.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000009785.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR AlphaFoldDB; S4RX45; -.
DR STRING; 7757.ENSPMAP00000009785; -.
DR Ensembl; ENSPMAT00000009826.1; ENSPMAP00000009785.1; ENSPMAG00000008887.1.
DR GeneTree; ENSGT00940000153408; -.
DR HOGENOM; CLU_066460_0_0_1; -.
DR OMA; ICENCMF; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245300}.
FT DOMAIN 46..112
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 253 AA; 29278 MW; 961FAB8E9126CD0C CRC64;
MPAIMTMLGD HTARQLLDFS QRLDINLLDS VVSWLYQGEG PQQRMAQEVL THLKEHPDAW
TRVDTILEFS QNMNTKYYAL QILENVIKTR WKILPRNQCD GIKKYVVGLV IKTSQEPINL
EKEKVYIGKL NMILVQILKQ EWPKNWPTFI SDIVGASRTS ESLCQNNMAI LKLLSEEVFD
FSSGQLTQFK AKHLKDSMCN EFSQVFQLCQ FVMENSQNAP LVAATLETLL RFLNWIPLGY
IFETKLISVL VYK
//
