ID   S4S1R8_PETMA            Unreviewed;       307 AA.
AC   S4S1R8;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Purine-rich element binding protein Aa {ECO:0000313|Ensembl:ENSPMAP00000011410.1};
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000011410.1, ECO:0000313|Proteomes:UP000245300};
RN   [1] {ECO:0000313|Ensembl:ENSPMAP00000011410.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the PUR DNA-binding protein family.
CC       {ECO:0000256|ARBA:ARBA00009251}.
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DR   AlphaFoldDB; S4S1R8; -.
DR   STRING; 7757.ENSPMAP00000011410; -.
DR   Ensembl; ENSPMAT00000011456.1; ENSPMAP00000011410.1; ENSPMAG00000010429.1.
DR   GeneTree; ENSGT00950000183162; -.
DR   HOGENOM; CLU_057873_1_1_1; -.
DR   OMA; WAKFGST; -.
DR   OrthoDB; 1040548at2759; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032422; F:purine-rich negative regulatory element binding; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 3.10.450.700; -; 1.
DR   Gene3D; 3.30.2450.30; -; 1.
DR   InterPro; IPR006628; PUR-bd_fam.
DR   PANTHER; PTHR12611; PUR-TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR12611:SF0; PURINE-RICH BINDING PROTEIN-ALPHA, ISOFORM B; 1.
DR   Pfam; PF04845; PurA; 1.
DR   SMART; SM00712; PUR; 3.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245300}.
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          105..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          276..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        276..294
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   307 AA;  33398 MW;  615502FAAF159069 CRC64;
     MADRDSGSEQ GAAGGSGGGG IMHPLQQQQQ QQETQELASK RVDIQNKRFY LDVKQNAKGR
     FLKIAEVGAG GSKSRLTLSM SVAVEFRDYL GDFIEHYAQL GPSSAMSGGG GGGGGGGGGI
     GSGGDHQSHH QQLQPDEPRR ALKSEFLVRE NRKYYMDLKE NQRGRFLRVR QTVSRGPGLG
     AQGQTIALPA QGMIEFRDAL AKLIDDFGVD EEPAELPEGT AVTVDNKRFF FDVGSNKYGV
     FMRVSEVKPS YRNSITVPLK AWAKFGATFS RYSDEMKKIQ EKQREKRAEP LEEEEGGGGG
     GDDGEED
//