ID S4XUH0_SORCE Unreviewed; 1296 AA.
AC S4XUH0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=SCE1572_17800 {ECO:0000313|EMBL:AGP36184.1};
OS Sorangium cellulosum So0157-2.
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=1254432 {ECO:0000313|EMBL:AGP36184.1, ECO:0000313|Proteomes:UP000014803};
RN [1] {ECO:0000313|EMBL:AGP36184.1, ECO:0000313|Proteomes:UP000014803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So0157-2 {ECO:0000313|EMBL:AGP36184.1,
RC ECO:0000313|Proteomes:UP000014803};
RX PubMed=23812535; DOI=10.1038/srep02101;
RA Han K., Li Z.F., Peng R., Zhu L.P., Zhou T., Wang L.G., Li S.G.,
RA Zhang X.B., Hu W., Wu Z.H., Qin N., Li Y.Z.;
RT "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline
RT milieu.";
RL Sci. Rep. 3:2101-2101(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CP003969; AGP36184.1; -; Genomic_DNA.
DR RefSeq; WP_020735503.1; NC_021658.1.
DR STRING; 1254432.SCE1572_17800; -.
DR KEGG; scu:SCE1572_17800; -.
DR PATRIC; fig|1254432.3.peg.4029; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR HOGENOM; CLU_006367_0_0_7; -.
DR OrthoDB; 5476032at2; -.
DR Proteomes; UP000014803; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR43671:SF13; LD04361P; 1.
DR PANTHER; PTHR43671; SERINE/THREONINE-PROTEIN KINASE NEK; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 17..299
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT COILED 1153..1203
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1296 AA; 138935 MW; 77AFCF541EC8EB0D CRC64;
MSSARIEPAR PLIAGRFHIE REVGRGGIGT VHRAYDVQTE RHVALKIITA LGVDAEGQAR
LSREGQILSE LDHPGIVRVV AFGTVDSTTT DAEGRRIEEG TTFIAMEWLD GEDLASRQRR
SPLSLREGLE VGRQVASALA TAHDAGVVHR DIKPSNILLL RGPPDAGIRV KLVDFGVAAS
KEVVLTTDAG SPVGTPAYIS PEQARGDATV DARSDLYSLG ATLFELVAGR PPHMGPTSIA
TLVRLATTPA PRLSEFLLDV VPALDELIHA LLLADRGLRP SSAREVADRL AALVAEPHLP
TPSPLRVSDN PPGVMGTRLV TTIVALHVAT GEERHRELEA LRRRGADALP LGADSIVAHL
GVRQAHGDEA SRALELGLGL GDRGGRVGVA SGRMRVDRTR SAGEVVDRAV ALAREAGLGR
VLADATTVEL SRGRFLGEPL DSGAVRVLSR APKRPDAQTP FVGRDAELIT TVAAFDRCVE
DRTPVVASIS GPPGIGKSRL AREFVARIAD RPDPPRLVQL RCESFGRAQA LGVATDALRV
LMGLPKGASL EQADEAVRAR RLLHGDGGLL ARLLANQPFP DGVDLRGARD ALYLSMTDIA
VGAASIEPCA LLVEDAQWAD PESVAWLDHL LGRATGRALF IMLMVRPAFW RDQGQRFTGR
DHVRVELRPI ARRATREIAR AVFSAAAAAR PFDEATLDRV AQQAAGSPLF AEELARVIAS
GKDAATAPTI EAAIQVSLDA LDEPTREAVV RMSVFGLSVW DVGLAEVGVA EPETALKKLI
AAELLVEQPA SRFTAAHEFL FKHALVRDVA YASVGEELRK KLHAAAARWL DRLGEDSATV
AQHFDLGGEH EEAAIRWEAA ARRALATNSL RDAVTMADRA LVFSPDKPTA FARAVLLEEA
YSRLDARSPE RDSAIRAMWE NVYDEASELR TLTARARYDH ACGSGMDLEG RLTALRDRAR
TIDLVEEEAQ CSATLAQVHA FAGQLAMAEQ EAAHLLDLAA RRGLVWAAVD AWQTRAVAHQ
TRGEPAAALE ARRNAARAAR RAGLQEREAM LTMNVGFALT TIGARGEALQ EIEAGIARAQ
AIGSSGAARH GQMILLCWVA TFGPEPRLDA ALAEPRASAD EAAGSMWVVR DRVTLGILFY
RGCELLRVES SGLARARSLL KKATEAYRVT ENRDVLPVAL GFCAEAERRF GNAEQAREIA
REAAALVEAG APSLLNEAPI YLALHDACVD MGDLVGAREA MERAMPPLLR RLKGLEGTPY
ASSFLLNLPQ NSALLVAAEA YGCVPPSLEA MMSSRP
//
