ID   S4Y3S7_SORCE            Unreviewed;       608 AA.
AC   S4Y3S7;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGP37523.1};
GN   ORFNames=SCE1572_25340 {ECO:0000313|EMBL:AGP37523.1};
OS   Sorangium cellulosum So0157-2.
OC   Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX   NCBI_TaxID=1254432 {ECO:0000313|EMBL:AGP37523.1, ECO:0000313|Proteomes:UP000014803};
RN   [1] {ECO:0000313|EMBL:AGP37523.1, ECO:0000313|Proteomes:UP000014803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=So0157-2 {ECO:0000313|EMBL:AGP37523.1,
RC   ECO:0000313|Proteomes:UP000014803};
RX   PubMed=23812535; DOI=10.1038/srep02101;
RA   Han K., Li Z.F., Peng R., Zhu L.P., Zhou T., Wang L.G., Li S.G.,
RA   Zhang X.B., Hu W., Wu Z.H., Qin N., Li Y.Z.;
RT   "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline
RT   milieu.";
RL   Sci. Rep. 3:2101-2101(2013).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; CP003969; AGP37523.1; -; Genomic_DNA.
DR   RefSeq; WP_020736988.1; NC_021658.1.
DR   AlphaFoldDB; S4Y3S7; -.
DR   STRING; 1254432.SCE1572_25340; -.
DR   KEGG; scu:SCE1572_25340; -.
DR   PATRIC; fig|1254432.3.peg.5740; -.
DR   eggNOG; COG1032; Bacteria.
DR   HOGENOM; CLU_448256_0_0_7; -.
DR   OrthoDB; 9804952at2; -.
DR   Proteomes; UP000014803; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd01335; Radical_SAM; 1.
DR   CDD; cd02068; radical_SAM_B12_BD; 1.
DR   Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR036724; Cobalamin-bd_sf.
DR   InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR   InterPro; IPR034466; Methyltransferase_Class_B.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR   PANTHER; PTHR43409:SF17; MG-PROTOPORPHYRIN IX MONOMETHYL ESTER OXIDATIVE CYCLASE 66KD SUBUNIT; 1.
DR   Pfam; PF02310; B12-binding; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR   SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR   SMART; SM00729; Elp3; 1.
DR   SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS51332; B12_BINDING; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00022485};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT   DOMAIN          28..161
FT                   /note="B12-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51332"
FT   DOMAIN          193..418
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|PROSITE:PS51918"
FT   REGION          12..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          578..608
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   608 AA;  67185 MW;  43D6DE797F751A7D CRC64;
     MRIALLYPPP WKIPAPGEAP DTSGDGPPAD YREGDLDPDF HQTPYGLYSL GAQAIRAGHQ
     VKVLNLSSYP FSQVERVVRE LDADVFGMSC WTANRRGVAL TARSIRRLHP AAHIVVGGPH
     ATPLAAEMLR HHPEIDTVAL GESELAFLEL LERLEAGRPA LGIAGTAYRV DGRVELGPPR
     AAIEDLDALE SPHDHYATHI VMTSRGCPWA CTFCGAETTW GRGFRGQSVP YVLDALEAAV
     NKLPVKMVQI KDDTFTTNRK RVIDICRGIR ERKISFLWSC DTRVDVLGDD LLREMRLAGC
     QRLSLGVESG SPSILKNIDK KITVKKIIES TELAKKYGIQ VRYYMMLGNR GETAETFRET
     LAFLEAAKPH QYIFSCLSIY PGTRDFDDAE AAGWLEREVY FRGDFQELKT PFDASEEDTA
     LMSAWFEQNK GLRELYREGV EERRAILARL GDHHAAHLEL GIAYLDAGQL DLAARHAARA
     LELGYPLPGL AHNALACVAA ARRDWQAMQD HFTAAAKRDP QHAVLIRNVQ AARAWYAKGG
     PDRGLPLDLV ARCDFQLLER TAQPALPGPL PEDFAVWPPA APRPAPARPA EAGGREAAAQ
     RGRLRVVP
//