ID S5M1E7_9MOLU Unreviewed; 696 AA.
AC S5M1E7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE SubName: Full=PTS system glucose-specific IIBC component {ECO:0000313|EMBL:AGR41867.1};
GN Name=ptsG {ECO:0000313|EMBL:AGR41867.1};
GN ORFNames=SDIMI_v3c01630 {ECO:0000313|EMBL:AGR41867.1};
OS Spiroplasma diminutum CUAS-1.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC Spiroplasma.
OX NCBI_TaxID=1276221 {ECO:0000313|EMBL:AGR41867.1, ECO:0000313|Proteomes:UP000014983};
RN [1] {ECO:0000313|EMBL:AGR41867.1, ECO:0000313|Proteomes:UP000014983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CUAS-1 {ECO:0000313|EMBL:AGR41867.1};
RX PubMed=23873917; DOI=10.1093/gbe/evt108;
RA Lo W.S., Ku C., Chen L.L., Chang T.H., Kuo C.H.;
RT "Comparison of metabolic capacities and inference of gene content evolution
RT in mosquito-associated Spiroplasma diminutum and S. taiwanense.";
RL Genome Biol. Evol. 5:1512-1523(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP005076; AGR41867.1; -; Genomic_DNA.
DR RefSeq; WP_020836100.1; NC_021833.1.
DR AlphaFoldDB; S5M1E7; -.
DR STRING; 1276221.SDIMI_v3c01630; -.
DR KEGG; sdi:SDIMI_v3c01630; -.
DR PATRIC; fig|1276221.3.peg.160; -.
DR eggNOG; COG1263; Bacteria.
DR eggNOG; COG1264; Bacteria.
DR HOGENOM; CLU_012312_1_0_14; -.
DR InParanoid; S5M1E7; -.
DR Proteomes; UP000014983; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR NCBIfam; TIGR00826; EIIB_glc; 1.
DR PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR PANTHER; PTHR30009:SF20; PTS SYSTEM GLUCOSE-SPECIFIC EIICB COMPONENT-RELATED; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000014983};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..573
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT DOMAIN 610..692
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT ACT_SITE 632
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 696 AA; 75223 MW; 21F5DDFB6A9D6B0F CRC64;
MKNISQKTGE KSENKFVGKM KSFGSGIMPT LSKLSKAFLL PIALLPIAGV FLGVGAAISS
NTDAGTFGFY FGSVLNKMGD VCFGNLPVLF CISVALAYTK DSGIAALTAV VGFLVMNGMQ
AALLHTQSVD PSTVWVQIDG NEWKKLIFDA NKNINWEEMG IGLQQITKWV SASNLEEIQN
NSAIVVNSNF ELIDGAGSVY YSLLWIDKIP NGLITSNIGV QSLNTGVFAG IFVGAIAAKC
YNKFHDTQLP SAISFFSGTK LVPIITFVAV IPLSFIFMFL WPYLGMGLAA FGKASGKLPV
GLDSFIYEIA ERSLVPFGLH HVFYAPLWWT NAGGSIAEAF TNVSAEDQAK FVNVWLQNHA
NLAGLIVGST PEEQFASISK LIQTQYNDLW TAMGDQTIAY KVIANTEVLN FKDLDALGLN
IGRFQSGKFG FMLFGLPMAG LAMWLNVPKE NRKSVMGIYF SAAFTCFLTG ITEPIEYTFL
FLAPWLFYGV HMPLAAISFL ITGALRTHVS MTVSGGFIDY IVFGIVPFFG SNAMSAKSVF
GVLGVAAVMA PAYFFSFYFA VKYGKVMVPG RDGSADVKLA SKADYKASKG QNLDGSKIKS
SKDSNEEARM EKATKIIEFL GGEENIVDVD ACASRLRLTV KDGSLVNKDS IIALGGATGA
LVKGTNIQIV YGGEQEAIKP RMIKILDEQR KAKQAK
//
