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Database: UniProt
Entry: S5MAC6_9MOLU
LinkDB: S5MAC6_9MOLU
Original site: S5MAC6_9MOLU 
ID   S5MAC6_9MOLU            Unreviewed;       443 AA.
AC   S5MAC6;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   20-JUN-2018, entry version 38.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01020005};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AGR40698.1};
GN   ORFNames=STAIW_v1c00010 {ECO:0000313|EMBL:AGR40698.1};
OS   Spiroplasma taiwanense CT-1.
OC   Bacteria; Tenericutes; Mollicutes; Entomoplasmatales;
OC   Spiroplasmataceae; Spiroplasma.
OX   NCBI_TaxID=1276220 {ECO:0000313|EMBL:AGR40698.1, ECO:0000313|Proteomes:UP000014984};
RN   [1] {ECO:0000313|EMBL:AGR40698.1, ECO:0000313|Proteomes:UP000014984}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT-1 {ECO:0000313|EMBL:AGR40698.1};
RX   PubMed=23873917; DOI=10.1093/gbe/evt108;
RA   Lo W.S., Ku C., Chen L.L., Chang T.H., Kuo C.H.;
RT   "Comparison of metabolic capacities and inference of gene content
RT   evolution in mosquito-associated Spiroplasma diminutum and S.
RT   taiwanense.";
RL   Genome Biol. Evol. 5:1512-1523(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP005074; AGR40698.1; -; Genomic_DNA.
DR   RefSeq; WP_020833837.1; NC_021846.1.
DR   EnsemblBacteria; AGR40698; AGR40698; STAIW_v1c00010.
DR   KEGG; stai:STAIW_v1c00010; -.
DR   PATRIC; fig|1276220.3.peg.1; -.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000014984; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000014984};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014984}.
FT   DOMAIN      134    268       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      351    420       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     142    149       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   443 AA;  50863 MW;  856152F850F4741B CRC64;
     MTNTILWKKI KEWLISSDLI EPNVYEEYIK NAFLEDLSNN QKAIIVNTEL SKWYLESIHS
     DIKEKMSNFV EKDIDILFLT SDEFKKEKKI KDIITKKNKT NISQDYLFDN FISGSSNINA
     LNASIGIAEN LGTKWNPLFI YGDSGLGKTH LLKAISNKVN NSNLALNVKY YTSLDFRKEI
     LESLMDGFKE IESTKEKMNS IDVLLIDDIQ FLANSGKTNE IFFNLFNSFI ENNKQIVLTS
     DKFPEHLNGF DKRLISRFSQ GLSVKIESPD LQTAINIIEY KIKIANIFLS PESIKYIASY
     FGTDVRKLEG IINKIEFYII QDKQESTNRI ELDKILKILE DYSFAPSGEV TIQKIKSVVA
     LNYGINIKAI DSNLRLQNVV KARHVAMYLT GEILKKNYSE IGIAFGGKDH TTVINAYNKI
     NKFLKEDKLF KNTLKKIKKE IIS
//
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