ID S5VB48_STRC3 Unreviewed; 899 AA.
AC S5VB48;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Beta-mannosidase {ECO:0000313|EMBL:AGS67747.1};
GN ORFNames=B446_04595 {ECO:0000313|EMBL:AGS67747.1};
OS Streptomyces collinus (strain DSM 40733 / Tue 365).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1214242 {ECO:0000313|EMBL:AGS67747.1, ECO:0000313|Proteomes:UP000015423};
RN [1] {ECO:0000313|Proteomes:UP000015423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40733 / Tue 365 {ECO:0000313|Proteomes:UP000015423};
RA Ruckert C., Szczepanowski R., Goesmann A., Pross E.K., Musiol E.M.,
RA Blin K., Wohlleben W., Puhler A., Weber T., Kalinowski J.;
RT "The complete genome sequence of Streptomyces collinus Tu 365.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AGS67747.1, ECO:0000313|Proteomes:UP000015423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40733 / Tue 365 {ECO:0000313|Proteomes:UP000015423};
RX PubMed=24140291; DOI=10.1016/j.jbiotec.2013.10.004;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Iftime D.,
RA Musiol E.M., Blin K., Wohlleben W., Puhler A., Kalinowski J., Weber T.;
RT "Complete genome sequence of the kirromycin producer Streptomyces collinus
RT Tu 365 consisting of a linear chromosome and two linear plasmids.";
RL J. Biotechnol. 168:739-740(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; CP006259; AGS67747.1; -; Genomic_DNA.
DR AlphaFoldDB; S5VB48; -.
DR STRING; 1214242.B446_04595; -.
DR KEGG; sci:B446_04595; -.
DR PATRIC; fig|1214242.5.peg.956; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_005015_2_4_11; -.
DR Proteomes; UP000015423; Chromosome.
DR GO; GO:0052761; F:exo-1,4-beta-D-glucosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR043534; EBDG/EBM.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041351; Ig_GlcNase.
DR PANTHER; PTHR43536; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43536:SF1; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF18368; Ig_GlcNase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000015423};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..899
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039002077"
FT DOMAIN 117..184
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 226..337
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 782..891
FT /note="Exo-beta-D-glucosaminidase Ig-fold"
FT /evidence="ECO:0000259|Pfam:PF18368"
FT REGION 17..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 97562 MW; 0DF77D436F5907B2 CRC64;
MGAVLLSLLG TLATGAWAGP RDQRPAPHEH RHAPSVTHVP ATAGSATPLS GYAIRSTADV
TDSAAAVSSP GYRADGWYPA GSRSTVLAAL LADGVYPDPF HSTDQQKIPR DDFQVPWWYR
SDFTVEDTGP RTRLDFSGVV SAADVYVNGH QVAGAADVTG AYTRHELDIT SLVRSGTNTV
AFRVRPNDPN KHLTMGWLDW LQPPPDRNMG LVRDVLVRRD GPVVLRDAHV VGELAVPALD
TADLTVRARA RNDSGTPVTA EVTGSVAGTR LTRSVPLAAH ETKTVTFSPA DVPGLHLTAP
KVWWPAGMGG QPLYDLDLAV SVSGAVSDTA HERFGIRDVR APLNADGARQ YRINGRRLLI
KGGGWSPDEF LRWDAGYVED RLRYALDLGL NTIRLEGHIE PDEFFDLADR LGVLTLPGWE
CCDKWEGQVN GGSESGEKWT ESDYPVAKAS MAAEAARLRR HPSVISFLIG SDAAPDARIE
KDYLDALGAA DWPVPVVPAA SDRSSPQLGR SGMKMTGPYE WVPPDYWYAK REGGATGFNS
ETSAGPDIPT LDTLRRMMTP AELDTLWKDP AARQYHRSPS TVFGTLKIYD AALTGRYGAP
AGLTDYVRKA QLAQYENVRA QYEAYGRNAT DASKPATGVI YWMFNSGWTS LHWQLVDRYL
DQGGAYFGAK KANEPLHIQY SYDDRSVVVV NNRHGSTGPL TARATLFDPD GTQRYDRTVT
GMTVDGDGAH GTALTLPSSV SGLPPTYLLR LTLTDADGRE VSRNVYWLST RADKLDWAHT
DWYYTPVTGY ADLRGLTSMA RVPVSAAAST VTSGDTSTTT VTVRTTGDGR TPSLLTDVHL
VDAQGRPVLP VRWSDNEVSL WPGETATLTA TYRTADLHGS APRVRVSGWN TPERTVPAA
//
