ID S5XU79_PARAH Unreviewed; 493 AA.
AC S5XU79;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Nucleobase:cation symporter-2, NCS2 family {ECO:0000313|EMBL:AGT08752.1};
GN ORFNames=JCM7686_1651 {ECO:0000313|EMBL:AGT08752.1};
OS Paracoccus aminophilus JCM 7686.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=1367847 {ECO:0000313|EMBL:AGT08752.1, ECO:0000313|Proteomes:UP000015480};
RN [1] {ECO:0000313|EMBL:AGT08752.1, ECO:0000313|Proteomes:UP000015480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 7686 {ECO:0000313|EMBL:AGT08752.1};
RX PubMed=24517536; DOI=10.1186/1471-2164-15-124;
RA Dziewit L., Czarnecki J., Wibberg D., Radlinska M., Mrozek P., Szymczak M.,
RA Schluter A., Puhler A., Bartosik D.;
RT "Architecture and functions of a multipartite genome of the methylotrophic
RT bacterium Paracoccus aminophilus JCM 7686, containing primary and secondary
RT chromids.";
RL BMC Genomics 15:124-124(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CP006650; AGT08752.1; -; Genomic_DNA.
DR RefSeq; WP_020950390.1; NC_022041.1.
DR AlphaFoldDB; S5XU79; -.
DR STRING; 1367847.JCM7686_1651; -.
DR KEGG; pami:JCM7686_1651; -.
DR PATRIC; fig|1367847.3.peg.1632; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_8_2_5; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000015480; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015480};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 22..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 493 AA; 51423 MW; 8C793D564567750B CRC64;
MQTDSTPKGF DPVEERLPAP RLFALGFQHV LVMYAGAIAV PLIVGRALQL DAKDVAFLIS
ADLFVCGIVT IIQSFGATQW FGIKLPVMMG VTFAAVGPMV AIASSNPGTE GARMMFGAIM
AAGVISIFFA PLVSRMLRFF PSVVTGTVIL VIGVSLMPVG INWIFGLPVG PTAPKIVDPA
QAEWLQTAIA AGGVPDGVKL LPTVPNPAYA SMTSILIGVV VLASILLIAR FAKGFVANIA
VLLGIIIGGL LAAALGVMHF GDIGSAAWFA PIKPMHFGTP IFDPIMILTM LLVMFVTMIE
STGMFLALSD ICERKMTPKA LSAGLRVDGL GTAIGGLFNT FPYTSFSQNV GLVGVTGVRS
RFVCVAGGAI MILLGLIPKM GALVESLPTT VLGGAGLVMF GMVAATGVRI LSNVDFKGNK
HNLFIVAVSL GLGMIPMIAP DFNQWLPHSV HTLIHSGILL AALAAVGLNW FFNGAPHANE
DDIRAAGHAA EAH
//
